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Content archived on 2024-06-16

Neonatal estimation of brain damage risk and identification of Neuroprotectants

Objective

NEOBRAIN is a project that brings together SMEs, industry and academic groups devoted to the diagnosis, management, and neuroprotection in newborns with perinatal brain damage. The focus of the project is the prevention of hypoxic-ischemic and inflammation-associated brain damage mainly observed in preterm newborns.
The objectives of the project are
1. to generate marker profiles of damage in multiple animal models and in human preterm infants using genomic/genetic, proteomic, and metabolomic approaches, as well as imaging and electrophysiologic modalities;
2. to develop neuroprotective strategies by identifying candidate molecules for intervention using such markers and molecules in animals;
3. to implement a clinical platform for an observational clinical epidemiologic study in human infants designed to contribute to objective #1 above and to transfer insights gained in objectives #1 and #2 from the animal to the human level;
4. to prepare for drug testing by using the project structure as a clinical platform for initial steps in clinical testing of interventions discovered.
We further envision developing the clinical platform in a fashion so it can serve as the basis for a subsequent large scale pan-European perinatal neuroprotective research initiative (Euro-Neo-Net, EURAIBI) that will enable us in the future to conduct additional clinical studies building upon the knowledge gained in NEOBRAIN.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-LIFESCIHEALTH-7
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

MEDIZINISCHE HOCHSCHULE HANNOVER
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (17)

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