Objective
Bovine babesiosis is a tick-borne disease mainly caused by the intraerythrocytic parasites Babesia bovis and B. bigemina. It affects cattle in tropical and subtropical regions, severely limiting meat and milk production. New tools are needed for its efficient control, including better surveillance in the face of control measures and development of improved vaccines. The main scientific objective of this work is to provide a molecular characterization of different B. bovis and B. bigemina field isolates that infect cattle in Mediterranean and Latin American countries, to detect their differences and similarities, in particular regarding identification of sequence polymorphisms in genes that codify for surface antigens that were previously defined as potential vaccine and diagnostic candidates. The main technological objective is to develop and test new diagnostic methods for bovine babesiosis in the participant countries. The specific aims are: a) Collection of blood samples from B. bovis and B. bigemina-naturally infected cattle from Argentina, Brazil, Mexico, Spain, Italy, Portugal and Turkey; b) Production of biological clones from some of the isolates collected; c) Studies of genetic and antigenic polymorphisms in genes codifying for already defined vaccine and diagnostic candidates; d) Definition of molecular markers and techniques that can be useful for strain characterization; e) Studies of alternative reservoirs among other ruminants and wildlife species for B. bovis and B. bigemina and f) Development of new diagnostic methods, including cELISA, strip tests and Real Time PCR, and comparison of their effectiveness with other available diagnostic tests. Accomplishment of these goals will provide new biotechnological tools and useful information about these parasites, which will contribute to the improved control of bovine babesiosis.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences microbiology protozoology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- agricultural sciences animal and dairy science domestic animals animal husbandry
- natural sciences biological sciences zoology mammalogy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-INCO-DEV-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ALCALÁ DE HENARES
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.