Objective
The proposed project aims at the development of a new paradigm for the integration of proteomics data into systems biology. The goal is to gain relevant knowledge on biological processes that are important for human health and to use this knowledge for the purpose of disease modelling. The strategy to achieve this objective is an innovative, explorative systems biology approach both on the molecular and physiological level with a strong focus on protein function and modification. The project will produce the necessary proteomics data indispensable for the identification of novel circulating protein factors and post-translational protein modifications that are important for the onset, dynamics and progression of complex diseases. Data generation will be complemented by the development of computational analysis methods for these novel data types and creation of adequate modelling technology. The project will benefit from the utilisation of established mouse disease models, existing benchmarking modules for computational analysis and the functional genomics platforms developed by and accessible to the partners. The consortium aims to demonstrate the newly developed technologies in a proof-of-principle study in an obesity-induced type-2 diabetes mouse model. The project consortium is headed by an SME and completed by four academic partners and one additional SME from three European countries. This composition of commercial and academic interests guarantees high-level scientific research as well as a strong focus on the commercial relevance and exploitation of the project results. Thus the proposed project will strengthen Europe's scientific and commercial competitiveness in the field of systems biology, which is one of the key technologies in future medical and pharmacogenetics research.'
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- medical and health sciences clinical medicine endocrinology diabetes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-LIFESCIHEALTH-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BERLIN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.