Skip to main content

Contribution of molecular epidemiology and host-pathogen genomics to understand Chlamydial trachomatis disease

Objective

Chlamydia trachomatis (CT) infections are responsible for both the world leading cause of blindness (trachoma) and the most prevalent sexually transmitted disease which is strongly associated with pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. Preliminary twin study-based findings of members of this consortium estimate that there is a 40% genetic predisposition to CT infections. In order to fully exploit human genomics in the battle against CT infections, it is necessary to reliably determine aforementioned genetic predisposition at the gene level to CT infection and to define a genetic fingerprint that can be used as a marker for this predisposition. The EpiGenChlamydia CA aims to structure trans-national research to such degree that comparative genomics and genetic epidemiology on large numbers of unrelated individuals can be performed.

Call for proposal

FP6-2005-LIFESCIHEALTH-6
See other projects for this call

Funding Scheme

CA - Coordination action

Coordinator

Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patientenzorg, Waarvan Uitgaat vu Medisch Centrum (Vu University Medical Centre)
Address
De Boelelaan 1105
Amsterdam
Netherlands

Participants (18)

Academisch Medisch Centrum Bij de Universtiteit van Amsterdam
Netherlands
Address
Meibergdreef 9
Amsterdam
Beckman Research Institute of the City of Hope
United States
Address
1500 East Duarte Road
Duarte, California
Erasmus Medical Center
Netherlands
Address
Dr. Molewaterplein 40
Rotterdam
Health Protection Agency
United Kingdom
Address
Holborn Gate, 330 High Holborn
London
Helsingin Yliopisto
Finland
Address
Yliopistonkatu 4
Helsinki
London School of Hygiene & Tropical Medicine
United Kingdom
Address
Keppel Street
London
Microbiome Ltd
Netherlands
Address
Troubadoursborch 59
Houten
Morehouse School of Medicine
United States
Address
720 Westview Drive, Sw
Atlanta
Municipal Health Service
Netherlands
Address
Nieuwe Achtergracht 100
Amsterdam
National Eye Care Programme
The Gambia
Address
Medical Headquarters
Banjul
National Institute of Public Health and the Environment
Netherlands
Address
Antonie Van Leeuwenhoeklaan 9
Bilthoven
National Public Health Institute
Finland
Address
Mannerheimintie 166
Helsinki
STI Aids Netherlands
Netherlands
Address
Keizersgracht '390'
Amsterdam
Skejby Sygehus, Aarhus University Hospital (Aarhus Universitetshospital)
Denmark
Address
Norrebrogade 44
Stiftelsen for Industriell og Teknisk Forskning Ved Norges Tekniske Høgskole
Norway
Address
Strindveien 4
Trondheim
The Chancellor, Masters and Scholars of the University of Oxford
United Kingdom
Address
University Offices, Wellington Square
Oxford
Universiteit Maastricht
Netherlands
Address
Minderbroedersberg 4-6
Maastricht
Uppsala Universitet
Sweden
Address
Sankt Olofsgatan 10B
Uppsala