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Content archived on 2024-05-29

Improved treatment of pain, depression and fatigue through translation research

Objective

Pain, depression and fatigue are subjective clinical manifestations of advanced cancer. Control of these symptoms is pivotal for quality of life of millions of palliative care patients. Pain is the most feared symptom for many patients. the prevalence of depression varies from 6-58% in palliative care patients, reflecting lack of standardised calidated methodology for its assessment in these patients.
Cachexia is likely to be the most important contributor to fatigue in palliative care. The plethora of other symptoms, comorbidities and the high age of most palliative patients support the need for evidence based management strategies. To improve management of pain, depression and cachexia in cancer patients it is necessary to provide new knowledge through research in several areas.
The research plan of the EPCRC will be based upon questions raised in the clinic, with focus on cancer palliative care patients, thus a "true" translated approach is chosen. The research will focus both on diagnosis and classification of these symptoms and understanding fo the underlying (causes) of their biology. to reach the aims of EPCRC it requires a multidisciplinary approach including basic scientists and clinicians that will translate human genome data into practical applications for these patients.
Assessment and classification of pain, depression and cachexia (fatigue) are the basis for diagnosis and subsequent treatment. By use of modern methods of molecular biology in the project we will increase the understanding og the role of genetic variability for pain and cachexia. European evidence based internet guidelines will be developed by members of the EPCRC supported by an international advisory board.
By recruiting a pan European panel, cultural, social and language barriers will be taken into consideration in the early phase of the guideline development.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-LIFESCIHEALTH-6
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Funding Scheme

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STREP - Specific Targeted Research Project

Coordinator

NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
EU contribution
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Total cost

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Participants (10)

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