Objective
The proposal presented here combines a series of training objectives that are specifically suited for the candidate fellow with a cutting-edge scientific study. The study aims to investigate the mechanism of stem cell niche maintenance in plants. Stem cells are the source of cells for organ development and regeneration in multicellular eukaryotic organism. A key question is how different signals integrate to maintain the correct position and size of the stem cell population and to coordinate proper meristem function. In the shoot meristem, the stem cells are specified by WUSCHEL (WUS)-dependent signals from underlying organizing centre cells, and transcriptional control of the WUS gene is a key regulatory switch in temporal and spatial stem cell regulation. Therefore, understanding the transcriptional regulation of WUS will give us insight in the mechanisms of how the boundaries and the position of the stem cell niche are stably maintained within the proliferating cellular context of the shoot meristem. We propose to perform an innovative genetic screen and a yeast-one-hybrid screen to identify transcriptional regulators of WUS, and to characterize their function in the stem cell niche in detail. Results will provide insight into plant stem cell regulation but also contribute to our knowledge in broader stem cell biology and have potential applications in biotechnological modification of plant growth and development. By undertaking this study, the candidate will have the opportunity to move to a different EU member state, to complement his background in plant physiology and molecular biology with a thorough experience in plant development and genetics, to experience working in a leading research group and to make a major step in his personal development. Together this will boost the scientific maturity and professionalism of the candidate and prepare him to work as an independent, competitive and innovative scientist in the near future.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences cell biology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences basic medicine physiology
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
FREIBURG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.