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Content archived on 2024-05-29

Genetic control of cell diversification into neuronal subtypes

Objective

Vertebrate development is orchestrated by the coordinated deployment of multiple and diverse programs of cell commitment and differentiation. One of the fundamental questions in this process is how a discrete number of transcriptional programs and extracellular cues combine to produce the enormous cellular complexity that characterizes vertebrate organisms. This research aims at uncovering the general principles of how cellular diversity is created in the sensory nervous system.

We aim to determine: 1/ the transcriptional programs directing the commitment and differentiation of different types of sensory neurons and 2/ how, when and where different types of sensory neurons are committed by genetic tracing. The proposed research takes advantage of multidisciplinary approaches including model systems and methods such as rapid screening of gene function in the chick, a boundary cap neural stem cell culture system, and advanced mouse genetics for revealing gene function and for lineage tracing.

Fields of science (EuroSciVoc)

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Keywords

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-MOBILITY-5
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

EIF - Marie Curie actions-Intra-European Fellowships

Coordinator

KAROLINSKA INSTITUTET
EU contribution
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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