Objective
In the mammalian brain, the neocortex plays a fundamental role in processing sensory information. While cortical areas responsible for processing different modalities may differ in some respects, the similarity of cortical microcircuitry across areas, and the ability of one area to take over the role played by another damaged area suggest that all neocortical areas may employ a single 'algorithm' for information processing.
This proposal will investigate the contribution of single cortical neurons to spontaneous and sensory-evoked neocortical activity. We have chosen to work with the auditory modality in rodents as presentation of sound stimuli is technically straightforward, and offers strong control over stimulus structure in the time domain.
Presently I have 4 years experience of in vivo whole-cell neuronal recordings. As part of this proposal, I will learn experimental and analytic approaches to studying multiple simultaneous neuronal activity in vivo with a leading research group in this field for 24 months. Newly-acquired skills will be returned to a research group in the EU during the final 12 months of the proposal.
A unique strength of this research proposal is our ability to combine several powerful new techniques - in vivo whole-cell patch clamp, multiple large-scale neuronal recordings with multi-site silicon microelectrodes, and novel analysis methods such as 'peer prediction' (Harris et al., Nature 424: 552-555) - to determine how anatomically-identified neurons are driven by, and contribute to, cortical network activity under different conditions of sensory stimulation.
This issue is of great importance for understanding the basis of cortical operation, and is likely to provide insights into the principles by which events in the outside world a re represented and processed by populations of cortical neurons.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry metalloids
- natural sciences computer and information sciences data science data processing
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.