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Light scattering investigation of bio-functionalised amphiphiles

Objective

This research proposal is aimed to investigate, by means of light scattering and other optical investigation methods, self-aggregation effects and interparticle interactions in solutions of bio-functionalized surfactants.

These compounds have an amphiphilic structure with biologically-inspired head groups (made for instance by a small number of nucleosides). As a consequence, they behave as 'smart' molecules capable of specific molecular recognition of a complementary head-group sequence, which makes them particularly appealing for the development of bio-nanotechnologies.

Indeed, by appropriate control of the chemical functionalities codified in molecular structure, bio-functionalized amphiphiles self-assembly as micellar systems, vescicles, microemulsions, 'living polymers', or chiral structures, and can be used to design host-guest complexes and systems for enzymatic confinement.

Main goal of the project is trying and establishing a link between the collective, non-specific, large-scale self-assembly phenomena that are usually investigated by soft matter scientists, and the short-range molecular specificity effects commonly seen as the driving force for association in biological fluids.

Call for proposal

FP6-2004-MOBILITY-11
See other projects for this call

Funding Scheme

ERG - Marie Curie actions-European Re-integration Grants

Coordinator

SOFT MATTER LABORATORY - NUCLEAR ENGINEERING DEPARTMENT (DIPARTIMENTO DI INGEGNERIA NUCLEARE) POLYTECHNIC OF MILAN (POLITECNICO DI MILANO)
Address
Via Ponzio, 34/3
Milano
Italy