Objective
The expertise in the rational design of nano-particles, mesoporous structures, hydro-gels, degradable polymers, aerogels, ceramics etc with variable bulk and surface chemical compositions and physicochemical properties has reached a climax but their potential use in the biotechnology industry has yet to be fully explored.
The detoxification of blood using enzymes and antibodies immobilised onto mesoporous materials (in a bioreactor specifically designed for this purpose) is one of the goals of this proposal, e.g. heparinase I, immobilised on periodic mesoporous organosilanes, to remove heparin from the blood.
The second is the use of nanomaterials, (degradable polymers, mesoporous supports and nanoparticles), in controlled release drug delivery systems. Many drugs, which are highly successful in selectively targeting diseases in a test tube, fail in clinical applications due to obstacles created by stability, delivery and potency in the body.
For example, RNA interference is a developing alternative treatment for many diseases but RNAi will not survive in the bloodstream and so the design and synthesis of a suitable delivery vehicle (degradable polymer to encapsulate and protect the RNA molecule) is essential if this treatment is to have future applications.
The world leading research group in controlled release drug delivery is at MIT and the aim of the researcher is to spend 2 years working with a range of experts in materials synthesis and drug release and capture under different conditions.
She would return to the MSSI, a materials institute in Ireland, whose ethos is the development of interdisciplinary skills for practical applications, to set up bioreactors for the detoxification of blood and initiate controlled release drug delivery studies using mesoporous materials, degradable polymers and other materials designed within the institute.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental biotechnology bioremediation bioreactors
- natural sciences chemical sciences polymer sciences
- natural sciences biological sciences genetics RNA
- engineering and technology nanotechnology nano-materials
- engineering and technology industrial biotechnology biomaterials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
n/a LIMERICK
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.