Objective
Among the most fundamental objectives in modern brain research is the identification of the basic processes and mechanisms responsible for information processing, learning and memory. Many different hypotheses and conflicting models for this unsolved issue have been proposed, however, there is a wide consensus in the field that changes in synaptic connections among neurons in a network play a crucial role.
Animal experiments over a period of 30 years have shown that changes in synaptic conductivity depend in a precise way on the time difference between action potentials in presynaptic and postsynaptic cells. This effect has been called spike-time dependent plasticity (STDP). The final aim of the present project will be to uncover the role of spike-time synaptic plasticity in synchronization and information transport in single units and in small neuronal networks.
The approach will be mainly theoretical but it will build on experimental measurements of single neurons from the rat cortex using the dynamic clamp recording technique. By combining neurobiology, computational modelling, nonlinear dynamics and time series analysis, the origin of robustness and flexibility will be investigated at three different levels of organization: from the smallest identified neuronal subcircuits via individual neurons up to small microcircuits made up of a limited number of neurons and synapses.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences computer and information sciences data science data processing
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
ROMA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.