Objective
This research proposal is focus on the integration of different high-pressure CO2-based processes: extraction / fractionation with CO2-assisted impregnation of polymers.
Two case studies, with a high potential for commercial application as nutraceuticals (according to preliminary studies carried out at the host laboratory) will be addressed:
- Coenzyme Q10 extraction from tobacco leaves and encapsulation in polyethyleneglycols. Coenzyme Q10 play an important role in cell respiration, electron transfer, ATP production, and modulation of oxidative reactions acting as antioxidant. It is actually synthesized and used for cosmetics or medicinal purposes.
- Policosanol extraction from sugar cane molasses and impregnation of lipidic matrices. Policosanols are also widely used as nutraceuticals due to their beneficial properties as cholesterol and triglyceride lowering compounds.
Firstly (as WP 1), Coenzyme Q10 and precursor molecules, such as solanesol will be extracted from tobacco leaves and separated (concomitant with extraction) from nicotine. Purified extracts will be encapsulated in polyethylene glycol.
Secondly (WP 2), hydroalcoholic extractions of policosanols from sugar-cane molasses will be performed followed by fractionation in counter current CO2 columns and impregnation of lipidic solids.
The final step will be common and up scaled for both 1 and 2 processes (WP3), namely the incorporation of both type of extracts into melts and particle formation by rapid expansion (pilot plant scale).
Therefore, extraction and impregnation or encapsulation would be performed in a continuous way (GRAS, no CO2 disrupted to the atmosphere, no use of organic solvents).
This means that the developed process might substitute the tedious, chemical- and time-consuming protocols utilized nowadays.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences polymer sciences
- natural sciences chemical sciences organic chemistry alcohols
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CAPARICA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.