Objective
Typically organisms face simultaneous attack from numerous pathogens. Despite this, interactions between different parasite species within the same host have not been investigated extensively. Studies indicate that competition for host resources between parasite species in the same host does occur, but the importance of this competition for disease evolution remains largely unresolved. In particular competition between different parasite species may have important implications for the levels of virulence experienced by the host population.
Greater understanding of within-host dynamics between interacting parasite species should therefore help us understand what factors affect virulence and the extent to which parasites can manipulate and overcome the host immune system.
This knowledge will have important implications for medical intervention strategies and the biological control of pests. We propose to study within-host competition between two microsporidian parasites (Vavraia culicis/Edhazardia aedis) in the Aedes aegypti mosquito-parasite model system. The mosquito Aedes aegypti is vector of a number of human diseases including dengue and yellow fever.
Through comprehensive experimentation we will elucidate how infection with two parasite species affects various life-history traits of the host and how parasite growth and virulence are affected through time. This project will employ a wide range of experimental techniques to tackle and understand the evolution of virulence in mixed infections.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries agriculture agronomy plant protection
- social sciences sociology demography mortality
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine immunology
- natural sciences biological sciences zoology invertebrate zoology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MONTPELLIER
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.