Objective
Standard genetic analysis in model organisms focuses on laboratory-induced mutations in single genes with large phenotypic effects. However, most of the variation that we see in natural populations is due to the sum of small effects, caused by naturally occurring alleles. Each allele (or variant gene) contributes to a particular trait and are known as quantitative trait loci (QTLs). Recent advances in genomic science has made these loci accessible for the first time in several model species, such as Arabidopsis.
The primary scientific objective of this project is to define and identify loci responsible for natural variation in shoot apical meristem and leaf growth. The project is based on the recent discovery of geographic cline in leaf growth variation that is based on progressive increased cell size. Using a combination of cellular, molecular and bioinformatics techniques and recombinant inbred lines, the major QTLs will be determined and mapped. Identification of candidate genes and the affected pathways will provide insight into the adaptive significance of this characteristic. The project will provide advanced training in a number of research areas, including high-resolution imaging, plant development, molecular biology and project design and management.
The results will be of use to botanists, ecologists, cellular and molecular biologists and environmental scientists. They will provide insight into the interaction between the environment and the plant genome at the most basic level and will inform a wide variety of disciplines from environmental ecology to predicting how plants might respond to climate change.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences ecology
- natural sciences biological sciences genetics mutation
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NORWICH
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.