Objective
Cancer is one of the worst killers in the world and a big burden on society. In Europe alone, there are 2.9 million estimated new cases and 1.7 million deaths each year. Tumour angiogenesis - the formation of new blood vessels and the remodelling of the existing vasculature in a solid tumour - has become the object of intense efforts of biologists and other scientists to understand, identify, and treat cancer. Imaging of cancer angiogenesis is important for early diagnosis, prognosis, and monitoring of new therapies that target tumour vasculature. Current non-invasive methods for imaging tumour angiogenesis (PET, CT, MR) have been proven inadequate. Over the past decade, microbubble contrast agents for ultrasound have matured from an investigational tool to a clinical tool capable of imaging flow at the level of microcirculation, both non-invasively and in real-time.
At the present, there are few, if any, methods available for the quantitative characterization of tumour vasculature morphology and flow. It is this problem on which we focus in the present work. The objectives of this work are to create high resolution tools for direct micro-vessel imaging and flow measurement in tumours, by developing 2D and 3D imaging and quantification methods with contrast enhanced diagnostic ultrasound. Applications beyond the liver and kidney, such as the breast, where inherently low flows present a scientific challenge will be addressed with maximum intensity projection techniques.
A rigorous teaching program will be established in the area of biomedical imaging at the University of Cyprus. Fundamental and applied research will be performed in both an academic and clinical environment with participants spanning from under- and post-graduate students, to visiting professors, and clinical researchers from Cyprus and other European countries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology
- medical and health sciences clinical medicine oncology
- engineering and technology medical engineering diagnostic imaging
- natural sciences mathematics applied mathematics numerical analysis
- natural sciences physical sciences acoustics ultrasound
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-10
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NICOSIA
Cyprus
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.