Objective
Many will argue that this will be the decade which unlocks the power of the biological membrane. It is the key element in the organisation and regulation of cells and therefore is of fundamental importance to biology. Allied to this, the ability to influence membrane behaviour (eg. by therapeutic intervention) or to harness the principles and components of membranes to technological applications (eg. biosensors) will usher in a new era of exploitation and innovative commercial development. This application is submitted in order to introduce into a rapidly emergent University in Ireland, a range of projects and their accompanying technologies associated with biological membrane science. It will at the same time bring to the whole of Ireland a major research unit dedicated to the study of biomembranes, a field which is under-represented in the Irish research portfolio. In so doing, it will inform and stimulate the community, provide a new focus for research and, most importantly, create a new skills base. This latter aspect is particularly relevant to the development of the private health sector where the greatest proportion of research invested is currently directed towards the membrane.
The protein systems to be studied are involved in cellular regulation (eg. G-protein coupled receptors, ion channels, lipocalin receptors) and membrane protein interactions and structure, many associated with defined diseases or human dysfunction. The areas of research will be structure/function relationships, protein interactions, protein folding and assembly, structural characterisation and cell biology.
The technologies to be employed include membrane protein expression, purification and reconstitution, membrane-directed 2-hybrid syste4ms, surface plasmon resonance, microphysiometry and the proteomics of membrane systems.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences condensed matter physics quasiparticles
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences biological sciences cell biology
- natural sciences biological sciences biochemistry biomolecules proteins protein folding
- natural sciences biological sciences genetics mutation
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MAYNOOTH
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.