Objective
Synchronization is a ubiquitous phenomenon in Nature, and has been considered as one of the engines of life in complex biological systems. Its study has originated new fundamental insights and analysis tools in both local and global dynamical models stemming from divergent disciplines. This proposal aims at determining the functional role of normal and aberrant synchronization mechanisms in the emergence of higher cerebral functions in health and disease, by using tools borrowed from nonlinear dynamics and complexity theory.
Specifically, the present proposal addresses the phenomenon of neuronal synchronization, at a wide range of spatial scales, as a major orchestrator of brain integration processes. To that end, it is necessary to understand how local and long-range interactions scale-up to a global activity in the brain. To accomplish this goal, we will recollect and analyze collective brain responses (multichannel-EEG, intracranial EEG, magnetoencephalographic recordings and local field potentials) and single-neuron activity under different normal and abnormal physiological conditions: from cognitive performance (sensory processing, attention, and memory in humans and non-human primates) to pathological mechanisms underlying Alzheimer's disease and epilepsy.
We will apply linear and nonlinear methods, as well as tools from stochastic analysis and from the theories of complex networks and delayed dynamical systems. Such approaches have proven to be very useful in the characterization of complex systems in generic models, and now will be applied for a better understanding of how higher cerebral functions arise in the normal brain. Results from this approach are expected to contribute in the early diagnosis of Alzheimer's disease and in the anticipation of epileptic seizures.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences zoology mammalogy primatology
- medical and health sciences basic medicine neurology epilepsy
- medical and health sciences basic medicine neurology dementia alzheimer
- natural sciences mathematics applied mathematics dynamical systems
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-NEST-PATH
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BARCELONA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.