Objective
Cell communication systems that form building blocks for biological computation devices have significant potential. They might be able within the human body to detect and respond to changes in the state of health and help to combat disease at an early stage or serve as sensors for detection of pollutants coupled to the ability to degrade dangerous substances.
CELLCOMPUT aims at providing proof of principle that complex devices consisting of two, three or more programmed cells can be designed and constructed and at generating building blocks for such devices. The project will design in silico cells that have the ability to communicate in predictable manner to form communication systems. The required cells will be constructed making use of re-engineered yeast signaling pathways - the pheromone response and osmosensing HOG pathway - for which certain synthetic biology building blocks have already been prepared. Re-engineering of the pathways will make use of systems biology approaches established in ongoing projects.
The systems will be constructed in yeast cells, improved in recursive manner integrating simulation of computational models and experimentation and their function will be demonstrated. In addition, the project will deliver approaches for systems reprogramming using highly specific mutations or chemical inhibitors. CELLCOMPUT aims at taking part in the development of synthetic biology in Europe through its research and training activities as well as its dissemination programme.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences synthetic biology
- natural sciences biological sciences genetics mutation
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-NEST-PATH
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
100 GÖTEBORG
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.