Objective
The ongoing outbreak of H5N1 highly pathogenic avian influenza (HPAI) has recently spread from Asia to Africa and Europe posing a real public threat as HPAI can occasionally infect humans. Ducks play a major role in the epidemiology of AI since wild water fowl, including ducks, constitute the natural reservoir of all subtypes of influenza and is considered as the "Trojan horse" of Asian H5N1 HPAI.
The NOVADUCK project brings together both private (2 companies, 1 SME) and public sector stakeholders (European reference laboratories and agencies on AI) from 4 European countries (France, Belgium, the United Kingdom and Hungary) towards the aim of developing and evaluating new highly protective and cost-effective avian influenza live vaccines for ducks, based on live vectors (pox viruses, Newcastle Disease Virus (NDV) & Duck Enteritis Virus (DEV)) and in line with the DIVA strategy (Differentiating between Infected and Vaccinated Animals). Viral vectors will be engineered to optimise both their immunogenicity and protective capacities. Vaccine candidates will be pre-screened for safety and immunogenicity using newly developed i duck-specific mmunological tools.
The best vaccine candidates will be evaluated for efficacy in a HPAI challenge-model in ducks. Serological DIVA test able to detect infection in vaccinated duck flocks will be generated and the effect of vaccination on genetic and antigenic drift of H5N1 will be assessed. The NOVADUCK project represents a significant opportunity to considerably boost European competitiveness in the field of AI.
The vaccines to be developed within the project should be efficient in domestic ducks as well as potentially in wild migratory ducks, swans and geese through a single mass administration (spray or drinking water). This could therefore have a tremendous impact in controlling the worldwide increasing dissemination of the virus up to its potential full eradication from the ecosystem.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental engineering water treatment processes drinking water treatment processes
- medical and health sciences health sciences public health epidemiology
- medical and health sciences health sciences infectious diseases RNA viruses influenza
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- natural sciences biological sciences ecology ecosystems
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-SSP-5-B-INFLUENZA
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LYON
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.