Objective Biological materials like blood, tissues and organs represent the hope for many medical situations but at the same time they pose a risk of transmitting diseases via blood transfusion, tissues transplantation or organ transplantation. Thus, there is an urg ent need to improve the technologies used for screening diseases such as HIV and hepatitis C. The same need exists to test donor blood in a cheap and fast way, especially in countries where the rate of infected blood is high due to high prevalence of diseases. In this project we will develop a very fast, cheap and at the same time very sensitive method which has the potential to detect more than 100 blood antibodies simultaneously. Within this project we focus on the detection of the presence of one of the pathogens HIV, HCV, HBV and syphilis in parallel. The presence of any of the mentioned blood pathogen is enough to exclude the donor that is suspected to have any of these pathogens in his blood. We are proposing an immunosensing diagnostic assay, based on the very specific immune reaction between antigen and antibody. A new type of surface plasmon resonance (SPR) transducing principle will be exploited which allows very fast and sensitive testing. The proposed innovation will be reached by developing a small desktop system which is easy to use and leads to accurate results within less than 5 minutes. The system will be tested in two countries against standard testing methods like ELIZA and PCR . The objectives of the SSP Work Programme will be achieved in multiple ways. This project provides a new testing method to prevent transmission of diseases by substances of human origin (SoHo). The testing method provides improvements in cost effectiveness, sensitivity and speed of testing. The resulting diagnostic system will represent a revolution in the field of rapid diagnostics and will reduce the risk of dealing with contaminated biological materials and will help to prevent persons to become severely ill. Fields of science medical and health scienceshealth sciencesinfectious diseasesDNA viruseshepatitis Bmedical and health scienceshealth sciencesinfectious diseasesRNA viruseshepatitis Csocial sciencespolitical sciencespolitical transitionsrevolutionsmedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health sciencesclinical medicinetransplantation Keywords method new SPR new SPR-method Programme(s) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) POLICIES-2.2 - Public health issues, including epidemiology contributing to disease prevention and responses to emerging rare and communicable diseases, allergies, procedures for secure blood and organ donations, non-animal test methods Call for proposal FP6-2005-SSP-5-A See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Address Hansastrasse 27 c München Germany See on map Links Website Opens in new window EU contribution € 0,00 Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS Hungary EU contribution € 0,00 Address Muegyetem rakpart 3. Budapest See on map Links Website Opens in new window GESELLSCHAFT ZUR FOERDERUNG DER ANALYTISCHEN WISSENSCHAFTEN E.V. Germany EU contribution € 0,00 Address Bunsen-kirchhoffstr. 11 Dortmund See on map Links Website Opens in new window HOCHSCHULE LAUSITZ (FH) Germany EU contribution € 0,00 Address Großenhainer straße 57 Senftenberg See on map Links Website Opens in new window HOLDING COMPANY FOR BIOLOGICAL PRODUCTS AND VACCINES (VACSERA) Egypt EU contribution € 0,00 Address 51 wizaret el-zeraa - agouza - giza - egypt Giza See on map Links Website Opens in new window MIKROMIKOMED KFT. Hungary EU contribution € 0,00 Address Késmrki u. 12. Budapest See on map MIVITEC GMBH Germany EU contribution € 0,00 Address Eichenstr. 24 Sinzing See on map Links Website Opens in new window THE UNIVERSITY OF BIRMINGHAM United Kingdom EU contribution € 0,00 Address Edgbaston Birmingham See on map Links Website Opens in new window UNIVERSITY OF REGENSBURG Germany EU contribution € 0,00 Address University str. 31 Regensburg See on map Links Website Opens in new window V.LASHKARYOV INSTITUT OF SEMICONDUCTOR PHYSICS, NATIONAL ACADEMY OF SCIENCE OF UKRAINE Ukraine EU contribution € 0,00 Address 41, pr.nauki Kiev See on map Links Website Opens in new window