Objective
One of the most dramatic changes in plant growth and development is the transition from life in the underground darkness after germination of the buried seed, to life in sunlight when the seedling reaches the soil surface. In Arabidopsis, seedlings in the dark have long hypocotyls, closed unexpanded cotyledons protected by an apical hook, and lack pigmentation.
Upon transition to light, seedlings switch their developmental program to adjust accordingly: the hypocotyl slows down elongation, the apical hook unfolds, cotyledons separate and expand, and chloroplasts develop and accumulate chlorophyll. Recent studies have shown that the phytochrome (phy) A and phyB photoreceptors, and the phy-interacting bHLH transcription factors PIF1 and PIF3 are involved in this process, together with the E3 ubiquitin ligase COP1. Despite increasing progress, the mechanisms operating in this dark-to-light developmental switch are still largely unknown.
The main objective of this proposal is to identify the regulatory mechanisms involved. Previous results have revealed the importance of the dark period in the regulation of this process. We propose to examine the protein and gene expression profiles during dark development in Arabidopsis seedlings to identify differentially regulated factors with a role in the dark-to-light switch.
The specific objectives are:
- identification of factors differentially expressed in dark-grown seedlings using a novel proteomics approach and through the analysis of genomic profiles; and
- characterization of the role of the new identified factors in the dark-to-light switch in development using reverse genetics and molecular approaches.
This proposal fulfils the objectives of the IRG Programme to contribute to European research and transfer the knowledge acquired by the applicant during the seven years of postdoctoral career in the US, and contributes to the objectives of the ERA to foster fundamental knowledge and basic tools for functional genomics.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-12
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BARCELONA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.