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Epidemiology and control of classical swine fever (CSF) in wild boar and potential use of a newly developed live marker vaccine.

Objective

Classical swine fever (CSF) is a recurring pathogen of domestic pigs in Europe, maintained in wild boar reservoir and reintroduced by contacts between domestic and free-living species. About 80% of the first outbreaks of CSF have occurred in regions where CSF in wild boar is endemic. However wild boars arena indigenous species in Europe and they should be managed as a part of our natural environment. Socially, large-scale outbreaks of CSF have a disastrous economic effect (billons of Euros), and public opinion perceives mass killings of animals as unethical. Animal welfare implications of CSF outbreaks are also serious. Currently, no live vaccine that can be differentiated from infection and adapted for young pigs is available. The objectives of the present project are:
(i) development of an epidemiological and economic model for CSF eradication in wild boar, (ii) adaptation of the classical C-strain oral vaccine for use in young wild boar,
(iii) development of a live marker vaccine for oral administration to wild boar and development of accompanied diagnostic assays. The expected results will be a complete package with an epidemiological tool to support wild boar management and CSF control. In addition an orally administrable live marker vaccine with accompanying discriminatory tests and sampling protocols will be developed that may come into action if preventive CSF control fails. Because CSF affects several European countries, a multinational and multidisciplinary research effort is appropriate and will contribute to realise the objectives of the priority thematic area: policy-orientated research.''

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug/vaccines

Call for proposal

FP6-2002-SSP-1
See other projects for this call

Funding Scheme

STREP - Specific Targeted Research Project
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Coordinator

CENTRUM VOOR ONDERZOEK IN DIERGENEESKUNDE EN AGROCHEMIE
Address
Groselenberg 99
Ukkel
Belgium

Participants (9)

FRIEDRICH-LOEFFLER-INSTITUT BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT
Germany
Address
Suedurfer 10
Greifswald - Insel Riems
INSTITUTE OF VIROLOGY, EUROPEAN COMMUNITY REFERENCE LABORATORY FOR CSF, SCHOOL OF VETERINARY MEDICINE HANNOVER
Germany
Address
Bünteweg 17
Hannover
ISTITUTO SUPERIORE PER LA PROTEZIONE E LA RICERCA AMBIENTALE
Italy
Address
Via Vitaliani Brancati 48
Roma
SWISS FEDERAL VETERINARY OFFICE
Switzerland
Address
Schwarzenburgstrasse 155
Bern
FORT DODGE VETERINARIA SA
Spain
Address
Carretera Camprodon S/n Finca "La Riba"
Vall De Bianya
UNIVERSIDAD COMPLUTENSE DE MADRID
Spain
Address
Avenida De Seneca, 2
Madrid
INSTITUTE FOR VETERINARY MEDICINAL PRODUCTS
Hungary
Address
Szàllàs
Budapest 10
CENTRAL AGRICULTURAL OFFICE, DIRECTORATE OF MEDICINAL PRODUCTS
Hungary
Address
Szallas 8
Budapest
STATENS VETERINÄRMEDCINSKA ANSTALT (THE NATIONAL VETERINARY INSTITUTE)
Sweden
Address
Ulls Väg 2B
Uppsala