Objective
Malaria remains one of the most successful diseases of human both in terms of its prevalence and of defying our attempts at control. Contributing to its success is the fact that its transmission fails to be prevented by the immune response of its human host or its mosquito vectors. Indeed, malaria parasites are only rarely killed by their mosquito vector's immune response in natural situations. One possible explanation for the lack of resistance is that the cost of the immune response prohibits the spread of resistance or that the parasites suppress the immune response. To study this phenomenon I have chosen an approach that mixes epidemiology and evolutionary ecology. The project will consist in determining links between the spatial variations in the epidemiological situation and several components of the mosquito's immune system and thus to evaluate possible costs of the constitutive and inducible immune responses and to determine how malaria parasites drive the selection of genes involved in the resistance of their mosquito vectors. Results of this work will help to determine if and under which conditions resistance of mosquitoes against malaria parasites can be selected. As transgenic mosquitoes are currently being designed to resist malaria parasites and are considered as a potential weapon to fight malaria, the proposed project has important implications for future malaria control.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences infectious diseases malaria
- medical and health sciences health sciences public health epidemiology
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
WAGENINGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.