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Functional analysis of DIR1, a putative lipid transfer protein that promotes long distance signalling during systemic acquired resistance in Arabidopsis.

Objective

Attempted infection can result in systemic acquired resistance (SAR)- the development throughout the plant of immunity to subsequent attack by a broad range of normally virulent pathogens. TheArabidopsis mutant defective in induced resistance 1-1 (dirl-1) exhibits wild-type local resistance toavirulent Pseudomonas syringe, but defence gene expression is abolished in distant leaves and dirl-1fails to develop SAR to virulent Pseudomonas or Peronospora parasitical. Petiole exudates experiments indicate that dirl-1 is defective in the production or transmission from the inoculated leaf of inessential mobile signal. DIR1 encodes a putative apoplectic lipid transfer protein (LTP) and we propose that DIR1 interacts with a lipid-derived molecule to promote long distance signalling. The proposed study will determine how the DIR1 protein functions and thus reveals how to enhance the capacity of plants to develop SAR. The main objectives are proposed to be the following :¿

Call for proposal

FP6-2002-MOBILITY-5
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Coordinator

JOHN INNES CENTRE
Address
Norwich Research Park, Colney
Norwich
United Kingdom