Objective Blood transfusion is universally practised in all European countries. Blood is a biologic material that has the potential to transmit diseases (e.g. HIV and, perhaps, vCJD). European citizens are becoming increasingly concerned about blood safety, despite improved screening and processing. Such concerns are making people reluctant to donate blood or receive it through transfusions. Safe, effective and commercially viable blood substitutes will overcome this problem.The EuroBloodSubstitutes Project brings together a multi-disciplinary, mixed gender team of experienced academic scientists, clinicians, industrialists and transfusion specialists to develop an integrated technological platform for generating blood substitutes for critical blood components, in particular oxygen carriers (novel prototype haem proteins), that will, longer-term, benefit all European citizens. The Project has a fundamental focus on novel, genomic-based approaches, involving the use of cell factories, for developing and optimising strategies for the efficient generation, modification, purification, biochemical and biophysical characterisation and physiological evaluation of prototype native, modified and variant haemoglobins for improved formulations of blood substitutes to replace some blood uses.The project will be informed by consultation and dialogue with lay (i.e. the public, patient groups), professional (clinical preservers and providers) and commercial (especially SME) stakeholders. The EuroBloodSubstitutes Project is directly relevant to the LifeSciHealth Thematic Priority of the 6th Framework Programme because it provides a baseline for integrating post-genomic research into biomedicaland biotechnological areas (generating prototype critical blood substitute components) that aims to stengthen European commerce (through blood substitute manufacture) and improve the future quality of life (through blood substitute use) for European people. Fields of science natural sciencesbiological sciencesgeneticsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVsocial scienceseconomics and businessbusiness and managementcommerce Keywords Blood substitutes haemoglobins haems proteins oxygen carriers protein expression Programme(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) LSH-2002-1.2.1-5 - Generation of blood substitutes for critical blood components, in particular oxygen carriers (hemopoietic stem cells are not in the scope of this line) Call for proposal FP6-2002-LIFESCIHEALTH See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator THE UNIVERSITY OF NOTTINGHAM Address University park Nottingham United Kingdom See on map Links Website Opens in new window EU contribution No data Participants (12) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITA DEGLI STUDI DI ROMA "LA SAPIENZA" Italy EU contribution € 0,00 Address Piazzale aldo moro 5 Roma See on map Other funding No data LUNDS UNIVERSITET Sweden EU contribution € 0,00 Address Paradisgatan 5c Lund See on map Other funding No data UNIVERSITA DEGLI STUDI DI MILANO Italy EU contribution € 0,00 Address Via festa del perdono 7 Milano See on map Other funding No data UNIVERSITA DEGLI STUDI DI PARMA Italy EU contribution € 0,00 Address Via universita 12 Parma See on map Other funding No data UNIVERSITY OF ESSEX United Kingdom EU contribution € 0,00 Address Wivenhoe park Colchester See on map Links Website Opens in new window Other funding No data SEMMELWEIS EGYETEM Hungary EU contribution € 0,00 Address Uelloi ut 26 Budapest See on map Other funding No data DANMARKS TEKNISKE UNIVERSITET Denmark EU contribution € 0,00 Address Anker engelundsvej 1, bygning 101a Lyngby See on map Other funding No data ALLIGATOR BIOSCIENCE AB Sweden EU contribution € 0,00 Address Scheelevagen, 19a Lund See on map Other funding No data LCC ENGINEERING & TRADING GMBH Switzerland EU contribution € 0,00 Address Steinbruchstrasse 43 Egerkingen See on map Other funding No data COMMON SERVICES AGENCY United Kingdom EU contribution € 0,00 Address Trinity park house, south trinity road Edinburgh See on map Other funding No data STICHTING SANQUIN BLOEDVOORZIENING Netherlands EU contribution € 0,00 Address An amsterdam See on map Other funding No data UNIVERSITE HENRI POINCARE NANCY 1 France EU contribution € 0,00 Address Rue lionnois 24-30 Nancy See on map Other funding No data
