Objective
The STREP will develop and improve tools and approaches to facilitate the generation of new knowledge in functional and structural genomic of viral Ranks. Specifically,
(I) new methods and tools for the rapid and efficient structural analysis of RNA and RNA/protein complexes will be developed,
(ii) these optimised tools will be applied to essential RNA elements that are vital for the function of HBV, HCV and HIV viruses, and
(iii) complementary screening techniques and structure analysis of RNA/legend complexes will be implemented to promote the identification of antiviral compounds targeting these RNA structures.
The project exploits availableness sequence data but will also expand our knowledge of viral RNA sequence elements and their variations. The biomedical importance of RNA as a research target is stressed by the fact that viral infections, such as HBV, HCV and HIV are major global public health problems. The outcomes of the project are expected to initiate the development of novel drugs that target viral RNA molecules and has thus strong implications for public health. The research consortium is strengthened by the involvement of an SME, which contributes a proprietary RNAscreening method. This SME will also function as a stakeholder to support the downstream application development towards RNA targeting drugs - even though this is beyond the scope of the current project. The project involves multidisciplinary research which is only possible by integrating, in an interdisciplinary fashion, the research capacities of a number of leading European labs, i.e. their equipment and complementary expertise on the structural, functional and virologist! Analysis of RNA and RNA/legend complexes. The innovative tools developed will be made available to other researchers throughout Europe and open the way for efficient analysis of a wide range of RNA-based processes extending far beyond analysis of viral Ranks.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences infectious diseases DNA viruses hepatitis B
- medical and health sciences health sciences infectious diseases RNA viruses hepatitis C
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- natural sciences biological sciences genetics RNA
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antivirals
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-LIFESCIHEALTH
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NIJMEGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.