Objective
BIOSCOPE will develop new scale-scale tools allowing unprecedented insight into bio-molecular mechanisms at biological interfaces on the scale of single molecules. The key element in the BIOSCOPE strategy is to involve the bimolecular system itself as part of the baroscopic instrument which in various ways reports to the out-side world about its current local state. BIOSCOPE benefits from the synergy between recent advances in Nan technology and the adaptive dynamic behaviour of many natural and artificial biological systems, which change their structure, physical chemical state and properties as a reaction to the local baroscopic environment.
The objectives of BIOSCOPE are
1.) To develop instrumentation and methods for manipulation of enzymes and enzyme activity at the scale-scale providing insight into the bimolecular mechanisms on a single molecule level.
2.) To develop novel forms of integration, at the level-level, of enzymes and non-biological systems such as Nan particles, artificial membranes, electrical field or force field traps.
3.) To confine several enzymes to surfaces of nanoparticles or membranes on a less than 10 nm scale in order to achieve a self-organized assembly with concerted as well as controllable bioaction superior to the simple sum of the same individual enzymes. This addresses NMP area 3.4.1.4 3.4.1.1 and 3.4.1.2.
The impact of BIOSCOPE is indeed envisaged as a long-term not only by providing new tools for the scientist, but also by making possible the rational design of new enzymes (and other proteins) based on their true bio-molecular mechanism. The knowledge-base provided by BIOSCOPE will allow researchers and industries to move from design of bimolecular systems based on end-state global properties, which is just one, some times distant, consequence of the true bimolecular mechanism. BIOSCOPE will provide new leads for major break-through in analyses and syntheses, which in turn will lead to the creation of several new SME.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences condensed matter physics soft matter physics
- engineering and technology nanotechnology nano-materials
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-NMP-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
117 LUND
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.