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Content archived on 2024-05-29

Development of a bioartificial pancreas for type I diabetes therapy

Objective

Four to five million people in Europe and about 80 million worldwide suffer from type 1 diabetes (insulin-dependent), characterized by a deficiency in insulin secretion resulting in hyperglycaemia responsible for debilitating long-term complications (coronary diseases, acquired blindness, chronic renal failures). Recently developed immunosuppressive protocols improved the success of humanallogenic pancreatic islets transplantation. However, such transplantation has severe limitations: the number of available donors and the potential toxicity of the immunosuppressive treatments. To avoidimmunosupression, islets could be encapsulated to protect them from the attack of the immune system and thus from rejection.
This project intends to develop, improve and validate an efficient reliablebioartificial pancreas for human application. To achieve this ambitious goal, various disciplines reintegrated in a true task force of basic and clinical researchers with leading expertise in experimental diabetes and advanced modern material technologies to develop an effective approach for the treatment of type 1 diabetes. The proposed approach takes into account the far-reaching advances in the modernnanosize technology, which are of utmost importance for the success of this challenge. To canny out the project to a successful achievement, the consortium gathers a multidisciplinary group of leading European scientists with complementary competencies, spending from biomaterials to tissue engineering, and high-tech Sees. This transactional approach provides convincing solutions to bypass the limitations of traditional treatments of this disease. That proposal fits perfectly within the scope of Priority Nan technologies and Nan sciences, 3.4.1 in particular Biotechnologies-biotechnologies, 3.4.1.2.Furthermore the proposal addressed also the 3.4.1.5 Application in areas such as health and medical systems, chemistry, energy, optics, food and environment.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2002-NMP-1
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

CENTRE EUROPEEN D'ETUDES DU DIABETE
EU contribution
No data
Address
Hopitaux Universitaires de Strasbourg, Boulevard Rene Leriche
STRASBOURG
France

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (13)

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