Objective The overall Science and Technology (S&T) objectives of this project are to create a knowledge base and technical platform that can be exploited in the design and development of Nan biotechnological processes and devices, tailored to steer/monitor cellular function. The project team consists of 7 leading groups in Europe, representing the necessary interdisciplinary competence and the complementarily required for this purpose. The project includes all levels from materials design and preparation, Nan structuring, chemical patterning, andbiomolecular interactions up to the cellular level. There are a number of obstacles, which currently prevent a knowledge base and a technical platform from being realised. Some relate to the lack of suitable fabrication methods e.g. to produce Nan patterned non-fouling surfaces with functional arrays of macromolecules, some relate to a lack of suitable characterisation tools e.g. tools to characterize the interface between living cells and synthetic materials, others relate to a lack of understanding of molecular interactions at surfaces and of mechanisms of cellular interactions at bio interfaces. The scientific and technical work plan addresses critical issues of the different types (fabrication, characterisation and understanding of molecular and cellular interactions. The main deliverables from this project will bei) new fabrication tools for scale-scale patterned surfaces,ii) new characterisation tools, andiii) knowledge generated of the interaction of biological systems components with scale-scale patterns and structures. This outcome will provide a platform for the design and implementation for directing cellular function via surface nano-scalemolecular cues. Fields of science medical and health sciencesmedical biotechnologycells technologiesstem cells Keywords Cellular biosystems Nanotechnology nanoscale surface cues smart biomaterials stem cells tissue culture Programme(s) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Topic(s) NMP-2002-3.4.1.2-1 - Interfaces between biological and non biological entities NMP-2002-3.4.4.2 - Tissue engineering, new biomimetic and bio-hybrid systems Call for proposal FP6-2002-NMP-1 See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator CHALMERS TEKNISKA HOGSKOLA AB Address Sven hultinsgata 2 Goeteborg Sweden See on map EU contribution € 0,00 Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all AARHUS UNIVERSITET Denmark EU contribution € 0,00 Address Nordre ringgade 1 Aarhus c See on map RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG Germany EU contribution € 0,00 Address Grabengasse 1 Heidelberg See on map UNIVERSITY OF GLASGOW United Kingdom EU contribution € 0,00 Address University avenue Glasgow See on map UNIVERSITE DE BORDEAUX I France EU contribution € 0,00 Address 351 cours de la liberation Talence See on map KAROLINSKA INSTITUTET Sweden EU contribution € 0,00 Address Nobels vaeg 5 Stockholm See on map EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Switzerland EU contribution € 0,00 Address Raemistrasse 101 Zurich See on map
