Objective
As a result of the Individual Marie Curie category-30 awarded to Or. Segovia, we have demonstrated that a genetic cell death programme pathway exists in phytoplankton, triggered when the cells are subject to different stress, but that in normal condition s is silenced. Considering the alarming ozone depletion that our planet is suffering, we propose to simulate the increase in UVB irradiation and examine its effects in cultures of several phytoplankton species, under laboratory and natural solar conditi ons. We will asses the ability of UVB to cause irreversible damage at the cellular level, affecting programmed cell death. The material aim of study will be cultured and short-term (h) exposed to different doses of UVB and simulating natural solar radiat ion with an ORIEL solar simulator which is one of the most important innovations in the study of photo biology. The ORIEL solar simulator simulates the solar spectrum with great accuracy, both for the upper part of the atmosphere and for the different oz one levels. Induction of cell death by UVB will be studied by means of: a) reduction in the number of cells, formation of pyrimidine dimmers, cellular viability, DNA condensation and fragmentation (hallmarks of the cell death process); b) detection of ca spases (proteases involved in the cell death process); c) study nutrient accessibility of the media under UVB radiation; and d) study of changes in CO2 fixation, c) and d) will help us to discriminate whether the effect of UVB on cell death is directly e xerted on the cell death genes or through stress provoked in the nutrient metabolism. This will be of great importance in the prediction of the ecological impact in terms of changes in the structure and functioning of marine ecosystems and processes in th e future, due to the genuine natural conditions imitated by the ORIEL solar simulator.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences marine biology
- natural sciences earth and related environmental sciences environmental sciences ozone depletion
- natural sciences biological sciences cell biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ESTEPONA (MALAGA)
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.