Objective
The objective of this proposal is to develop an entirely new, one-step process for the immobilization of proteins/enzymes or other biomolecules of interest, which is applicable on a large scale to surfaces of any kind. If successful, the new methodology wi ll offer several advantages over the classical immobilization techniques, including a better reproducibility, high flexibility, broad applicability, straightforward processing and thus potentially high throughput rates. The new way of processing may in tur n lead to entirely new applications which are not feasible with the current state-of-the-art technology. The method of immobilization to be investigated exists in the incorporation of biomolecules, and proteins in particular, in thin plasma polymerized coa tings. For that purpose, solutions containing these proteins or other biomolecules will be administered to a cold, atmospheric plasma together with either liquid or gaseous polymer precursors. Biomolecules may then be incorporated into very thin plasma pol ymer films and exposed to the surface where they exhibit their activity, providing they are not damaged by the plasma. The effect of the plasma on the structure and activity of biomolecules is largely unknown and it represents the main research topic of th is project. The bio-engineered materials to be obtained are envisioned to have bio-recognition sites, designed to specifically interact with other biological or non-biological species. Applications of such materials can be found in the medical, chemical, e nvironmental, food, materials and many other industrial sectors, including but not limited to bio-sensors, labs-on-a-chip, bio-mimetic materials, anti-microbial materials, intelligent materials, etc. In order to optimize the chances of success of this proj ect, which combines materials technology and biotechnology, a highly interdisciplinary team of researchers was put together.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences chemical sciences polymer sciences
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-NEST-A
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MOL
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.