Objective
The genetic code of humans and multiple other species has been identified. The critical experiments will be to identify the function of these genes in normal physiology and in diseases such as cancer. Genetic animal models have proven to be extremely valuable to elucidate the essential functions of genes.
In particular, the generation of transgenic mice and so-called gene targeted mice has provided novel insights into gene functions and the pathogenesis of disease. Using gene-targeted mice Penninger's group has identified a master gene, RANKL, of bone loss in arthritis and osteoporosis (Nature, 1999; Nature 1999; Cell 2000) and they identified genes that control heart size (Nature 2002;Cell 2002); cell death (Nature 1999 & 2001); cancer (Nature 2000); or pain (Cell 2002).
Based on impact factors, his laboratory has been ranked as one of the 10 best laboratories in the world as the only non-US based research group and Prof. Penninger was ranked among the 10 most promising young scientists in the world in all fields of Sciences. After 13 years in North America, the Austrian Academy of Sciences has now made Prof. Penninger and his group an offer to come to Vienna to continue his outstanding work at IMBA, a new Centre of Excellence founded by the Austrian Academy of Sciences.
Cancer care will be revolutionized over the next decade by the introduction of novel therapeutics that target the underlying molecular mechanisms of the disease. Prof. Penninger will bring his expertise in functional mouse genomics and biochemistry to Europe to create a new European centre of excellence.
A primary goal is to generate a platform for the development and application of functional genomics in order to understand the pathogenesis of malignancies and to provide new animals models to test and develop novel therapies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology prostate cancer
- medical and health sciences clinical medicine rheumatology
- medical and health sciences clinical medicine oncology breast cancer
- medical and health sciences basic medicine physiology
- medical and health sciences basic medicine medical genetics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-8
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VIENNA
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.