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Content archived on 2024-05-29

Micro surface science of materials for micro total analysis systems

Objective

With the advent of Micro-Electro-Mechanical Systems (MEMS), there is considerable potential for so-calledbio-MEMS devices - microsystems for the automated analysis and continuous processing of biological samples.Bio-chips Lab-on-a-chip, m-Total Analysis S ystems and Bio-sensors are some of the terms used todescribe bio-MEMS devices, and m-TAS is the term which is used throughout this proposal. The applications of m-TAS cover a broad range: point-of-care diagnostics, pharmacogenomics, high-throughput drug di scovery,forensics, food-safety, plant genomics, agriculture and military applications. m-TAS offer two key advantagesover existing macro-scale technologies: scale - large sample volumes of biofluids are not required; and speed - very high throughput can be achieved, with continuously-flowing, massively-parallel device. The StokesResearch Institute (SRI) located at the University of Limerick (UL), Ireland is currently active in micro TotalAnalysis System (m-TAS) research. A barrier to the present m-TAS resea rch stream is a lack of knowledge regarding the compatibility of bio-fluidicsamples with micro-device materials. Such specialist knowledge is vital in terms of the propagation of thevarious reactions which must take place in a m-TAS device, impacting on ef ficiency, and on contamination,impacting on usability and dependability.MicroSurfTAS a Marie Curie Host Fellowship for the Transfer of Knowledge is therefore proposed to impartknowledge centred on bio-fluid and surface interaction. The Fellowship will fun d one more experiencedresearcher to advance surface fluid compatibility knowledge, and two experienced researchers to address samplecontamination issues.The outcome of the Host Fellowship will be the acquisition by the SRI of materials biocompatibility and contamination expertise related to micro-systems for the processing of DNA.

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Keywords

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Topic(s)

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Call for proposal

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FP6-2002-MOBILITY-3
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Funding Scheme

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TOK - Marie Curie actions-Transfer of Knowledge

Coordinator

UNIVERSITY OF LIMERICK
EU contribution
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Address
South Circular Road
LIMERICK
Ireland

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Total cost

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