Objective
DNA methylatìon plays an essential role in regulating plant development: recent research has demonstrated that this epigenetic phenomenon plays an integral role in processes such as vernalisation, flowering and endosperm development. Even though the exploration of epigenetic phenomena has been intensively developed for the study of cancer and many human disease syndromes, only a few groups are studying these phenomena in plants, where they have major economic relevance, such as somaclonal variation or transcriptional gene silencing. Epigenetic regulation of gene expression is mediated by two processes: methylation of cytosine residues in DNA and chromatin structure. Dr Finnegan's group in CSIRO Australia is undoubtedly a world leader in this area, as it has a high international profile earned through many key contributions to plant epigenetic research over the last 10 years.
Dr Rival is the leader of a research group working on the molecular determinism of somadonal variation in tropical plants of economic importance, such as oil palm. The aim of the present OIF is to consolidate Dr Rival's expertise in the understanding and study of epigenetic mechanisms implants. Dr Rival's group has shown that the occurrence of floral variants in tissue culture derived oil palm is associated with DNA hypomethylation. The time is ripe to integrate the various strategies developed by Dr Finnegan's group to the study of epigenetic regulation of somadonal variation in oil palm.
The VARIOMETH fellowship will focus on the role of DNA methyl trans ferases on the determinism of somadonal variation and on the exploration of the relationship between DNA methylation and chromatin remodelling. Indeed, methylated DNA has been found to adopt a distinctive chromatin structure in the genome.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences genetics genomes
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds cereals
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-6
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
PARIS
France
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