Objective
Main objective is to develop an advanced platform for analysis of harmful micro organisms and/or their toxic products. The goal will be reached by integration of the data on genomes and proteomes available through bioinformatics and advanced silicon and m icrosystem technology. The platform, based on ambitious electric biochip arrays, will enable parallel and simultaneous identification and quantification of specific nucleic acids, microbial proteins and toxic microbial products. The targets are recognized and captured by DNA probes or antibodies on the electrochemical transducer surface, that are arrays of nm-sized interdigital gold electrodes The captured analyte molecules are labelled with an enzyme that produces an electroactive product thus generatin g an electric current that corresponds to the concentration of the target analyte in the sample. All application developing partners use this platform and same electrical read out instrumentation but they implement their special expertise into developmen t of specific innovative chip arrays. The DNA-and protein-arrays require different and specific procedures for chip loading of the recognition elements, and for detection. The equipment's will be portable devices and are furnished with disposable chips. The technique will be generic but the applications in the project are selected analyses of food and water born harmful micro organisms and microbial toxins: 1) Shiga toxin producing Escherichia coli (STEG, ETEC, EHEC etc); 2) Salmonella enteriditis 3) pa thogenic strains of Bacillus cereus, 4) pathogenic Staphylococcus strains that cause food poisoning and infections, 5) Legionella responsible for the Legionnaire's disease distributed via water, and 6) Mycotoxins. The diagnostic equipment is evaluated fo r functionality in different exploratory prototypes by a large industrial partner and a specialised SME, assessing the quality management issues for pharma/food/evironmental industry.'
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences biological sciences biochemistry biomolecules nucleic acids
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences genetics DNA
- natural sciences chemical sciences inorganic chemistry metalloids
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-LIFESCIHEALTH-I
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
STOCKHOLM
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.