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Understanding Diatom Biology by Functional Genomics Approaches

Objective

Diatoms are photosynthetic eukaryotes providing close to one quarter of global fixed carbon and approximately one fifth of the oxygen we breathe. Remarkably, very little is known about their basic biology and how it is affected by environmental change. The Diatomics project will address these issues in marine diatoms using information based on two completed diatom genome sequences. Important topics that will be addressed include carbon sequestration, nutrient acquisition, the rise and fall of algal blooms, and biofouling. We will study gene expression profiles at the whole genome level in response to ecologically-relevant stimuli, will manipulate expression of candidate key genes by reverse genetics, and will study phylogenetic histories and ecological significance of these genes in a range of diatoms. Ultimately, the project should lead to the development of non-neutral markers that can be used to assess diatom ecophysiology in natural environments in response to changing environmental conditions. Furthermore, a subset of diatom genes will be transferred into rice by an SME, with the aim of improving key agronomic traits. An improved understanding of diatom biology can also lead to advances in human health care and well-being.

Call for proposal

FP6-2003-LIFESCIHEALTH-I
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Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

STAZIONE ZOOLOGICA ANTON DOHRN
Address
Villa Comunale
Napoli
Italy

Participants (12)

MARINE BIOLOGICAL ASSOCIATION OF THE UK
United Kingdom
Address
The Laboratory, Citadel Hill
Plymouth
UNIVERSITY OF NANTES
France
Address
Quai De Tourville 1
Nantes
THE UNIVERSITY OF BIRMINGHAM
United Kingdom
Address
Edgbaston
Birmingham
LEIBNIZ INSTITUT FUER MEERESWISSENSCHAFFEN
Germany
Address
Wischhofstr. 1-3
Kiel
THE HEBREW UNIVERSITY OF JERUSALEM
Israel
Address
The Authority For Research And Development, Edmond J. Safra Campus, Givat Ram
Jerusalem
BIOINFOBANK INSTITUTE
Poland
Address
Limanowkiego 24A
Poznan
CROPDESIGN N.V.
Belgium
Address
Technologiepark 3
Zwijnaarde
UNIVERSITEIT GENT
Belgium
Address
Sint-pietersnieuwstraat 25
Gent
UNIVERSITY OF MELBOURNE
Australia
Address

Parkville
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
3 Rue Michel Ange
Paris
ECOLE NORMALE SUPÉRIEURE
France
Address
46, Rue D'ulm'
Paris
STIFTUNG ALFRED WEGENER INSTITUT FÜR POLAR UND MEERESCHFORSCHUNG
Germany
Address
Columbusstrasse
Bremerhaven