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Content archived on 2024-05-29

Scanning probe microscopy techniques for real time, high resolution imaging and molecular recognition in functional and structural genomics

Objective

High resolution ¡maging of living cells and subcellular components is essential for functional and structural genomics'. Scanning Probe Microscopy (SPM) has evolved into the imaging method of choice that yields the greatest structural details on biological samples such as proteins, nucleotides, membranes and cells in their native, aqueous environment and at ambient conditions. In addition, due to its high lateral resolution and sensitive force detection capability, the exciting possibility of measuring inte r- and intra-molecular forces of bio-molecules on the single molecule level has become possible, leading to new possibilities for the evolution of methods that will enable us to examine the physiological consequences of, even, the interaction of a single l igand molecule with its cognate receptor. In this project we propose to develop Scanning Probe Microscopy to advance the state of the art of this technique. With the support of the Sixth Framework program, Scanning Probe Microscopy is ready to become a mat ure imaging and measurement platform for cell biology that will become as widespread in the biomedicai laboratory as the confocal microscope, adding value to the European scientific instrument market and giving it a major presence worldwide.'

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2003-LIFESCIHEALTH-I
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

NoE - Network of Excellence

Coordinator

UNIVERSITEIT LEIDEN
EU contribution
No data
Total cost

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No data

Participants (9)

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