Skip to main content

Understanding the dynamics of cell division

Objective

This Research Network consists of nine teams that provide an interdisciplinary environment for training researchers in the field of eukaryotic cell division. The teams combine expertise in cell biology, biochemistry, proteomics, biophysics, chemical geneti cs, organic chemistry, and mathematics. The scientific goal of the joint research programme is to understand the dynamics of cell division and to discover inhibitors of mitosis with potential as anti-cancer drugs. The multidisciplinary network aims at over coming the fragmentation of research into the fields of spindle mechanics and cell cycle regulation, at bringing together laboratories working on different model organisms, and facilitating exchange between experimentalists and theoreticians. The network i ntegrates different tasks, for example identifying missing interaction partners of mitotic regulators and motor proteins, developing novel quantitative in vivo fluorescence microscopy assays, performing high-throughput screens of chemical libraries of smal l molecules to identify inhibitors and activators of mitotic proteins, and theoretical modelling of cell division. This Research Network is necessary, because understanding a complex biological process like cell division requires an integrated approach com bining various disciplines and techniques. The need is even more pressing, since diseases related to cell proliferation are a major unsolved problem in European societies and on a world-wide level. In conclusion, training by this Research Network will prep are the early-stage and experienced researchers for tackling complex biological systems like the cell division machine. Quite generally, they will have a qualification to address challenges in modern biology requiring interdisciplinary approches. They will be prepared for basic research and for work in the biomedical sector.

Call for proposal

FP6-2002-MOBILITY-1
See other projects for this call

Funding Scheme

RTN - Marie Curie actions-Research Training Networks

Coordinator

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Address
Meyerhofstrasse 1
Heidelberg
Germany

Participants (10)

BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM
Hungary
Address
Muegyetem Rkp 3-9
Budapest
CENTRE DE REGULACIÓ GENÒMICA
Spain
Address
Passeig Marítim, 37-49
Barcelona
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
3, Rue Michel-ange
Paris
FUNDAÇÃO CALOUSTE GULBENKIAN - INSTITUTO GULBENKIAN DE CIÊNCIA
Portugal
Address
Av.de Berna 45A
Lisboa
MAX PLANCK GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
Germany
Address
Hofgartenstrasse 8
München
PATERSON INSTITUTE FOR CANCER RESEARCH, CHRISTIE HOSPITAL NHS TRUST
United Kingdom
Address
Wilmslow Road
Manchester
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG.
Germany
Address
Seminarstrasse 2
Heidelberg
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Address
The Old Schools, Trinity Lane
Cambridge
UNIVERSITAET KONSTANZ
Germany
Address
Universitaetstrasse 10
Konstanz
UNIVERSITÄT LEIPZIG
Germany
Address
Ritterstrassse, 26
Leipzig