Objective The strategy of replacing DMA natural bases by non-polar surrogates has opened ways to add new functions to the DNA structure, to probe protein-DNA interactions, to test DMA repair enzymes, to stabilize structure, and to probe the internal features of the helix. Also, different fluorescent species named fluorosides, which have been shown an increasingly useful tool for bio-molecular analysis and is applied widely in the biosciences.This project wants to develop a new series of nucleosides with different characteristics. One group will have different steric demanding nucleosides which will be used to study the interaction with DNA polymerase enzyme and the other group will have fluorescent activity which will be evaluated as a molecular tags. Fields of science natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesgeneticsRNAnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-2.2 - Marie Curie Outgoing International Fellowships (OIF) Call for proposal FP6-2002-MOBILITY-6 See other projects for this call Funding Scheme OIF - Marie Curie actions-Outgoing International Fellowships Coordinator UNIVERSIDAD AUTÓNOMA DE MADRID Address Ctra. de colmenar km 15, cantoblanco Madrid Spain See on map Links Website Opens in new window EU contribution € 0,00 Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all DEPARTMENT OF CHEMISTRY STANFORD UNIVERSITY United States EU contribution € 0,00 Address 107 stauffer l building Stanford See on map Links Website Opens in new window
