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Supercritical carbon dioxide processing technology for biodegradable polymers targeting medical applications

Objective

This project will develop a highly innovative 'Supercritical fluid' processing technology that will enable European industries to develop and manufacture, in a highly controlled manner, advanced multifunctional biodegradable materials that posses consist ent and well defined physical and mechanical properties, chemical composition, porosity, and degradation profile. This technological advance will be realised through addressing the scientific and technological gap between fundamental academic research an d industry and through further developing advanced process control methodologies. The innovative processing technology developed within the project will also be designed to enable efficient integration with existing extrusion and injection moulding machi nes found throughout European industry. The key project objectives include: - The processing of porous biodegradable polymers that demonstrate significant weight reductions, but whilst retain the physical and mechanical properties of the compact materia l. - The processing of thermally and shear sensitive polymers, demonstrating significant improvements in the reduction of degradation during processing, without induced foaming. - To establish the fundamental relationship between the injection moulding variables and the surface and interior properties of the material, and to establish the parameters that lead to process control. - To achieve process control of the materials biodegradation profile. - To achieve scale-up and application of the processin g technology, with consistent and reliable process control. - To establish the limitations of material design due to the degradation that occurs during sterilisation, and to identify sterilisation best practice.

Call for proposal

FP6-2003-NMP-TI-3-MAIN
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Funding Scheme

STIP - Specific Targeted Innovation Project

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Address
Edgbaston
Birmingham
United Kingdom

Participants (6)

ARENA-ZME-LIMITED
United Kingdom
Address
Daniels Way, Hucknall Industrial Park
Hucknall, Nottingham
S.E. DE CARBUROS METALICOS, S.A.
Spain
Address
C/ Arag 300
Barcelona
SMITHERS RAPRA LIMITED
United Kingdom
Address
Shawbury
Shrewsbury
TECHNICAL UNIVERSITY OF LODZ (POLITECHNIKA LODZKA)
Poland
Address
Ks. L. Skorupki 6/8
Lodz
TREXEL GMBH
Germany
Address
Robert Wilhelm Bunsen Strasse 5
Gummersbach
UNIVERSITY OF TWENTE
Netherlands
Address
Drienerlolaan 1
Enschede