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Biosensors based on membrane organisation to replace animal testing

Objective

The ultimate goal is the development and validation of alternative techniques to replace animal testing in procedures concerning drug screening and environmental control. The first step is the organisation of a Specific Support Action that brings together fragmented industrial and academic research groups in a Strategic Meeting. In this meeting a powerful platform in biophysical chemistry and biosensor technology will be formed. A prospective analysis will be outlined for future developments of membrane-based biosensors validated by comprehensive inter-calibration techniques. A Work Programme consisting of a set of Work Packages will be produced, with the aims to channel the original research into useful economic and society benefits, which will support the Amsterdam Protocol on animal protection and welfare, 1986. The Directive states in Article 7: An experiment shall not be performed if another scientifically satisfactory method of obtaining the result sought, not entailing the use of an animal, is reasonably and practicably available. Almost 17 years have elapsed since the Amsterdam Protocol was written and since that time research on supported lipid membranes has become increasingly intense. Highly selective biomimetic membranes are now available for biosensing applications in general and for replacement of animal testing in particular. This will increase the options of meeting the requirements in Article 7 above and even carry them further. The participating research groups from Europe, Israel and USA, are centres of excellence in membrane and peptide production, biosensing, physicochemical modelling, surface characterisation, polymer technologies, bioassay techniques and multivariate calibration. The participating industries represent leading pharmaceutical and chemical companies using cutting-edge multivariate calibration techniques. The combination is unique and therefore the project has the potential to become world leading in this particular field.

Call for proposal

FP6-2003-LIFESCIHEALTH-I
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Coordinator

UMEA UNIVERSITY
Address

Umea
Sweden

Participants (15)

WARSAW UNIVERSITY
Poland
Address
Pasteura 1
Warsaw
UNIVERSITY OF LEEDS
United Kingdom
Address
Woodehouse Lane
Leeds
EBERHARD-KARLS UNIVERSITÄT TÜBINGEN
Germany
Address
Auf Der Morgenstelle 8
Tübingen
SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES
Sweden
Address

7070 Uppsala
VTT TECHNICAL RESEARCH CENTRE OF FINLAND
Finland
Address
Vuorimiehentie 5
1000 Espoo
LULEA UNIVERSITY OF TECHNOLOGY
Sweden
Address

Lulea
 
BOARD OF TRUSTEES, UNIVERSITY OF ARKANSAS
United States
Address
120 Ozark Hall, University Of Arkansas
Fayetteville, Arkansas
THE HEBREW UNIVERSITY OF JERUSALEM
Israel
Address
The Authority For Research And Development, Edmond J. Safra Campus, Givat Ram
Jerusalem
QUEEN MARY AND WESTFIELD COLLEGE, UNIVERSITY OF LONDON
United Kingdom
Address
Mile End Road
London
UNIVERSITAT DE LLEIDA
Spain
Address
Plaça Víctor Siurana 1
Lleida
DUBLIN CITY UNIVERSITY
Ireland
Address
Glasnevin
Dublin
UMBIO AB
Sweden
Address
Tvistevägen 22; C/o Uminova Innovation Ab
Box 7978 Umeå
ROSVALL INSTRUMENT
Sweden
Address
Sävvägen 16A
Surte
LHASA LTD
United Kingdom
Address
Department Of Chemistry, University Of Leeds
Leeds
BAYER AG, BAYER TECHNOLOGY SERVICES
Germany
Address
Bayerwerk Geb.e41
Leverkusen