Objective
The European Union, like the rest of the world, is faced with an epidemic of the related chronic conditions, Type 2 diabetes, obesity and the metabolic syndrome. Unless steps are taken to alleviate this crisis, the cost of treating the long-term consequences of these conditions could overwhelm our healthcare systems. Although genetic factors increase the risk of developing these conditions, their rapid current global rise must be due to environmental factors. Obesity and insulin resistance, both precursors of Type 2 diabetes, arise due to an imbalance between energy intake and energy expenditure. This in turn may be due to two features of the modern urban lifestyle: (i) frequent consumption of processed foods with high energy and low fibre content; (ii) reduction in the amount of exercise taken due to changes in social and transport patterns. It is now well established that regular exercise, combined with an improved diet, provides protection against the development of these conditions, as well as a first line of treatment. The aim of the consortium is to provide a better understanding of the molecular mechanisms involved, especially in terms of the signalling pathways and changes in gene expression, that provide these beneficial effects of exercise. Our consortium will address these questions using a range of multidisciplinary approaches including:
(i) molecular and cell biology;
(ii) studies of animal models;
(iii) physiological studies in human volunteers of both genders;
(iv) epidemiological and genetic studies of large human populations of both genders.
The consortium includes companies in the areas of food production, pharmaceuticals and biotechnology, who will ensure rapid application of the findings made. Improved understanding of the molecular basis of the beneficial effects of exercise will yield applications not only in these industries, but will also provide a sounder theoretical basis for policies regarding promotion of good health.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences cell biology
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences health sciences nutrition obesity
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-LIFESCIHEALTH-I
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
DUNDEE
United Kingdom
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Participants (25)
COPENHAGEN
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ICP-UCL 75.29 BRUSSELS
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PARIS
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2177 COPENHAGEN K
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KUOPIO
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BAGSVÆRD
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SÖDERTÄLJE
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LONDON
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MADRID
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BELLATERRA (CERDANYLOA DEL VALLES)
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PRAGUE
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LONDON
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616 MAASTRICHT
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PADOVA
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STOCKHOLM
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MUNICH
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NOTTINGHAM
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BIALYSTOK
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117 LUND
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LONDON
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CAMBRIDGE
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ROEDOVRE
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BP 53 GRENOBLE
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0396 GENTOFTE
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ZURICH
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