Objective Advanced cancer typically involves multiple symptoms and seriously affects patients´ quality of life. Anxiety and depression are common. Medical care for patients with advanced cancer should be aimed at symptom control, psychosocial support, spiritual needs, and practical issues. Patients’ preferences regarding care should be central. Open and respectful communication are of key importance, but have been found to be a challenge for health care professionals as well as patients and relatives. Advance care planning (ACP) is a formalised process of communication between patients, relatives and caregivers about patients’ care preferences. It raises awareness of the need to anticipate future deterioration of health. ACP can improve current and future health care decision making, provide patients with a sense of control, increase adequate symptom control and improve quality of life.This project aims to study the effects of formalized ACP on symptom burden and quality of life of patients with advanced cancer. In a phase III multicentre cluster randomized controlled trial at least 20 hospitals in 6 countries will be randomized to provide patients with advanced cancer with either ACP or ‘care as usual’. 1334 patients diagnosed with lung or stage IV colorectal cancer will be included. Patients will fill in questionnaires at inclusion, and at 2.5 and 4.5 months post-inclusion. A relative will fill in a questionnaire after the patient’s death. Use of medical care will be assessed through medical files. Primary endpoints are quality of life (QLQ-C30 emotional functioning) and symptoms at 2.5 months post-inclusion. Secondary endpoints are the extent to which care as received was in line with patients’ preferences, patients’ evaluation of the decision making process, quality of dying and cost-effectiveness of the intervention. Our project will assess the impact of ACP on quality of life, and contribute to improving comfort and quality of care for patients with advanced cancer. Fields of science medical and health sciencesclinical medicineoncologycolorectal cancer Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2013.2.4.1-3 - Investigator-driven supportive and palliative care clinical trials and observational studies Call for proposal FP7-HEALTH-2013-INNOVATION-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Address Dr molewaterplein 40 3015 GD Rotterdam Netherlands See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Administrative Contact J.Th.N. Koos Lubbe (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands EU contribution € 306 000,00 Address Heidelberglaan 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Administrative Contact Hans Van Delden (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data VRIJE UNIVERSITEIT BRUSSEL Belgium EU contribution € 658 602,00 Address Pleinlaan 2 1050 Bruxelles / brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Higher or Secondary Education Establishments Administrative Contact Nik Claesen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data ISTITUTO PER LO STUDIO E LA PREVENZIONE E LA RETE ONCOLOGICA Italy EU contribution € 511 225,00 Address Via cosimo il vecchio 2 50139 Firenze See on map Region Centro (IT) Toscana Firenze Administrative Contact Guido Miccinesi (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data THE UNIVERSITY OF NOTTINGHAM United Kingdom EU contribution € 386 208,00 Address University park NG7 2RD Nottingham See on map Region East Midlands (England) Derbyshire and Nottinghamshire Nottingham Activity type Higher or Secondary Education Establishments Administrative Contact Paul Cartledge (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITY OF LANCASTER United Kingdom EU contribution € 364 500,00 Address Bailrigg LA1 4YW Lancaster See on map Region North West (England) Lancashire Lancaster and Wyre Activity type Higher or Secondary Education Establishments Administrative Contact Roderick O'brien (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERZITETNA KLINIKA ZA PLJUCNE BOLEZNI IN ALERGIJO GOLNIK Slovenia EU contribution € 496 864,00 Address Golnik 36 4204 Golnik See on map Region Slovenija Zahodna Slovenija Gorenjska Activity type Higher or Secondary Education Establishments Administrative Contact Lea Ulcnik (Mrs.) Links Contact the organisation Opens in new window Other funding No data KOBENHAVNS UNIVERSITET Denmark EU contribution € 487 600,00 Address Norregade 10 1165 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Administrative Contact Bjarne Friis Ploumark (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
