Skip to main content

Collaborative REsearch on ACute Traumatic brain Injury in intensiVe care medicine in Europe

Objective

"Traumatic brain injury (TBI) is among the leading causes of death and disability and the main cause of death among the under-45s. Most patients with moderate to severe TBI are admitted to intensive care units (ICUs)
The “PROSAFE” ICU network was recently established in 6 European countries through EU funding (PHEA 2007331), and has continued to collect high-quality data beyond the grant duration. In 2011, 225 ICUs had joined PROSAFE, recruiting a total of 73,163 patients, 2,694 of whom were admitted for TBI. Hence the network can expect to enrol 7-9,000 moderate to severe TBI patients in 4 years. The PROSAFE consortium has already focused attention on TBI and has just started collecting additional information on this condition in order to develop a prognostic model to identify centres of excellence in TBI management
Aims of proposal are to consolidate the existing network in order to better describe the epidemiology of moderate-severe TBI in 7 countries (Greece has now joined the consortium); build a prognostic model based on short- and long-term outcome measures; identify most effective clinical interventions for optimally treating TBI patients, and recognize the determinants of optimal vs suboptimal performance
All TBI-CDEs endorsed by InTBIR will be collected, along with other items needed to develop a sensible prognostic model, permitting the consortium to join forces with international collaborative initiatives in the field
Availing of the coordinating institute’s biobank and consolidated expertise in biochemical and genetic biomarkers, the aim is to identify prognostic markers and underlying genetic factors influencing response to treatment and final outcome
The PROSAFE consortium is thus in a position to guarantee superior quality data collection in 7 countries and ensure it continues beyond the life of the project. These conditions are essential if the consortium is to contribute to Europe playing a key role in the success of the InTBIR initiative"

Call for proposal

FP7-HEALTH-2013-INNOVATION-1
See other projects for this call

Coordinator

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Address
Via Mario Negri 2
20156 Milano
Italy
Activity type
Research Organisations
EU contribution
€ 2 386 582
Administrative Contact
Guido Bertolini (Dr.)

Participants (8)

SEMMELWEIS EGYETEM
Hungary
EU contribution
€ 519 726
Address
Ulloi Utca 26
1085 Budapest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Akos Csomos (Dr.)
WARSZAWSKI UNIWERSYTET MEDYCZNY
Poland
EU contribution
€ 478 470
Address
Ul. Zwirki I Wigury 61
02 091 Warszawa
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Malgorzata Mikaszewska- Sokolewicz (Dr.)
SPLOSNA BOLNISNICA NOVO MESTO
Slovenia
EU contribution
€ 256 671
Address
Smihelska Ulica 1
8000 Novo Mesto
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Rafael Kaps (Dr.)
UNIVERZITETNI KLINICNI CENTER LJUBLJANA
Slovenia
EU contribution
€ 337 671
Address
Zaloska Cesta 002
1000 Ljubljana
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Miha žemlja (Mr.)
EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED
Cyprus
EU contribution
€ 314 645
Address
Makedonitisas Avenue 46
1700 Nicosia
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Theodoros Kyprianou (Prof.)
BEN-GURION UNIVERSITY OF THE NEGEV
Israel
EU contribution
€ 703 680
Address
.
84105 Beer Sheva
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Daphna Tripto (Ms.)
PANEPISTIMIAKO GENIKO NOSOKOMEIO IRAKLEIOU
Greece
EU contribution
€ 374 625
Address
Voutes
71110 Irakleio
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Dimitris Georgopoulos (Prof.)
OROBIX SRL
Italy
EU contribution
€ 71 280
Address
Via Gabriele Camozzi 144
24121 Bergamo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Luca Antiga (Dr.)