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Translating neuroimaging findings from research into clinical practice

Objective

Abstract 9
Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standardised set of NI and complementary demographic, clinical, cognitive, and genetic measures. The clinician will enter data on to an iPad, and these data, along with NI data will be electronically transferred to a central facility for analysis. Key features of the analysis include the assessment of NI data at a network level, the integration of NI and non-NI data, and the use of machine learning methods to make predictions specific to the patient being assessed. The results will be delivered to the clinician’s iPad and will indicate the likelihood of a given clinical or functional outcome. The tool will have 3 clinical applications. PSYSCAN-Predict will facilitate prediction of the onset of psychosis in high risk subjects. PSYSCAN-Stratify will aid early diagnosis and the stratification of patients with first episode psychosis according to future course and outcome. PSYSCAN-Monitor will allow clinicians to measure progression of the disorder over time. The tool will be developed and validated in 2 large scale naturalistic studies using the consortium’s extensive network of centres. The validated tool will then be disseminated to clinical centres across the EU. The PSYSCAN project involves a world-class consortium of experts on NI and psychiatry that unites academic centres, SME’s with image processing and computerised testing expertise, a large medical device provider, and the pharmaceutical industry. The consortium is thus ideally suited to translating expertise and knowledge in NI to build a tool that can be used to improve the care of patients with psychiatric disorders.

Field of science

  • /natural sciences/computer and information sciences/artificial intelligence/machine learning

Call for proposal

FP7-HEALTH-2013-INNOVATION-1
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

KING'S COLLEGE LONDON
Address
Strand
WC2R 2LS London
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 812 188,19
Administrative Contact
Paul Labbett (Mr.)

Participants (21)

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 603 802,65
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Janet De Vries (Mrs.)
CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Spain
EU contribution
€ 379 468,50
Address
Calle Monforte De Lemos 5
28029 Madrid
Activity type
Research Organisations
Administrative Contact
Manuel Sánchez (Dr.)
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 130 522,37
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renata Schaeffer (Ms.)
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 88 687,75
Address
Minderbroedersberg 4-6
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jim Van Os (Prof.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 237 826
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Noble (Ms.)
UNIVERSITY OF MELBOURNE
Australia
Address
Parkvilleoffice Of The Vice Chancellor
3010 Melbourne
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Melinda Heron (Ms.)
Servicio Cántabro de Salud
Spain
EU contribution
€ 182 869,70
Address
Avenida De Cardenal Herrera Oria
39011 Santander
Activity type
Research Organisations
Administrative Contact
Maria Blanca Urquidi Sandoval (Ms.)
REGION HOVEDSTADEN
Denmark
EU contribution
€ 52 399,98
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Martin Lund (Mr.)
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS

Participation ended

Germany
Address
Robert-koch-strasse 40
37075 Goettingen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christiane Hennecke (Ms.)
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
EU contribution
€ 84 661,44
Address
University Road
H91 Galway
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mari Vahey (Ms.)
IXICO TECHNOLOGIES LIMITED
United Kingdom
EU contribution
€ 1 217 973
Address
4Th Floor Griffin Court 15 Long Lane
EC1A 9PN London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Whitrow Jane (Dr.)
CAMBRIDGE COGNITION LIMITED
United Kingdom
EU contribution
€ 357 047,40
Address
Tunbridge Court Tunbridge Lane, Bottisham Cambs
CB25 9TU Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Deborah Tonge (Ms.)
Eli Lilly and Company Limited
United Kingdom
EU contribution
€ 124 696,95
Address
Lilly House, Priestley Road
RG24 9NL Basingstoke
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Trafford Clarke (Dr.)
F. HOFFMANN-LA ROCHE AG
Switzerland
EU contribution
€ 124 246,95
Address
Grenzacherstrasse 124
4070 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Olga Baiao-Feo (Dr.)
UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI
Italy
EU contribution
€ 106 368
Address
Viale Abramo Lincoln 5
81100 Caserta
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rosa Santo (Mrs.)
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 139 020
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
De Jong Freek
PHILIPPS UNIVERSITAET MARBURG
Germany
EU contribution
€ 35 000
Address
Biegenstrasse 10
35037 Marburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lois Woestman (Ms.)
MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER
Israel
EU contribution
€ 71 100
Address
Tel Hashomer Sheba Medical Center
52621 Ramat Gan
Activity type
Research Organisations
Administrative Contact
Eve Keret (Ms.)
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 64 460,78
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kasper Siegfried (Prof.)
UNIVERSITAT ZURICH
Switzerland
EU contribution
€ 101 011,92
Address
Ramistrasse 71
8006 Zürich
Activity type
Other
Administrative Contact
Sofia Karakostas (Ms.)
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
EU contribution
€ 84 994,42
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Julia Feuerer (Ms.)