Objective We propose an EID between Technion and IBM–Zurich, aimed at developing novel tools for biomolecular analysis and training the next generation of scientists and engineers who likely will translate the technologies and discoveries into practical use for the benefit of society and EU hi-tech sector.In vitro diagnostics is experiencing critical shifts in paradigms with a growing market which encompasses clinical laboratory tests, point-of-care devices, and basic research aimed at understanding the origin of diseases and developing improved testing and treatments. The development of novel tools, which enable increased analysis speeds, higher sensitivity, higher throughput, miniaturization, and portability are essential for enabling discoveries and providing better care for patients.We here propose three distinct yet synergistic projects for advancing biomolecular analysis. Each project is intended as a PhD project that integrates specific skills and know-how from both PIs and their respective institutes. The uniting theme of the projects is the use of microfluidics and isotachophoresis (ITP) to enable precise transport, focusing, and control of samples within micron-sized channels. ITP is an electrophoresis technique which allows focusing of species of interest on an electric field. Using ITP we create ~10 pL zones in which sample is focused, reacted or mixed. We term this concept “virtual vials”, and will combine theory, computation, and experimentation to create:1. “PCR shuttle” - a new method and device for rapid amplification of nucleic acids2. “Open space concentrator” - a new method and device for bioanalysis of tissue sections3. “low-voltage open-channel immunoassay” - a new method and device for point-of-care immunodiagnosticsWe strongly believe that students graduating from our joint Technion-IBM programme will be uniquely situated to lead, innovate, and collaborate on technological innovation in the European Community. Fields of science natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidicsnatural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsnatural scienceschemical scienceselectrochemistryelectrophoresis Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2013-ITN - Marie-Curie Action: "Initial Training Networks" Call for proposal FP7-PEOPLE-2013-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY EU contribution € 400 163,38 Address SENATE BUILDING TECHNION CITY 32000 Haifa Israel See on map Activity type Higher or Secondary Education Establishments Administrative Contact Mark Davison (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all IBM RESEARCH GMBH Switzerland EU contribution € 376 446,62 Address SAEUMERSTRASSE 4 8803 Rueschlikon See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Catherine Trachsel (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data