Objective
How sensory information is encoded by neuronal population activity in the brain, and how the pattern of activity is reshaped by experience constitute the fundamental questions in neuroscience research. In the current project, ‘OdorLearningCircuit’, we will address these questions with the rodent olfactory bulb (OB) as a model system. Although the odor-evoked neuronal activity in the OB has been extensively studied, less is known about how the population activity of each cell type is spatially organized in the OB, and how the organization is modified when animals actively use odor information to optimize their behavior. In this project, we aim to tackle these important issues by a combination of cutting-edge techniques: we will deliver genetically encoded Ca2+ indicators (GECIs) specifically to major types of neurons in the OB, and use 2-photon microscopy to map the neuronal population activity from awake mice performing an odor discrimination task under head-restrained condition. We will analyze how spatio-temporal pattern of odor-evoked population activity is dynamically remodeled in awake learning mice, at single-cell resolution and with cell-type distinction. The knowledge to be gained in the project will not only be important in the field of olfactory physiology, but also provide useful implications for understanding the general mechanisms underlying learning in other neural circuits.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences physical sciences optics microscopy
- social sciences sociology social issues social inequalities
- medical and health sciences basic medicine physiology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1211 Geneve
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.