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Content archived on 2024-05-28

Towards Biodegradable Nanoparticles: Hybrid Organic Mesoporous Silica

Objective

Despite their great potential, full exploitation of mesoporous silica nanoparticles (MSiNPs) as in-vivo multi-functional theranostic agents is still held back by the lack of a controlled and complete biodegradability. Indeed removal of nano-medical tools from the biologic system after the accomplishment of their diagnostic or therapeutic function still remains a pivotal, yet unresolved issue impeding their clinical translation. A most desirable design for improving the properties of nano-medical tools would hence involve their ability to hierarchically self-degrade into renally clearable products after carrying out their function. Thus, the ambitious aim of this project targets the synthesis of novel, specific, hybrid MSiNPs-based theranostic tools, able to perform their beneficial action and subsequently fragment in smaller pieces allowing easy execration via renal system. In this way, thanks to the combination of the intrinsic biocompatibility of MSiNPs, their ease of functionalization and the newly conferred enhanced biodegradability, a superior material adaptable to a wide range of diagnostic and therapeutic applications, with great promise for clinical translation, will be achieved.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2013-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

UNIVERSITE DE STRASBOURG
EU contribution
€ 97 023,30
Address
RUE BLAISE PASCAL 4
67081 Strasbourg
France

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Region
Grand Est Alsace Bas-Rhin
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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