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Statistical multi-Omics UNDerstanding of Patient Samples

Objective

Bioinformatic analysis is the biggest bottleneck in many genomic medicine projects. Our objective is to enable researchers to dramatically increase statistically informed use of personal multi-omic data in medicine. Soon, multiple types of omic technologies will be applied to 100,000s of patient-derived samples, with the three-stage goal of better understanding disease biology, discovery of new interventions, and personalizing the choice of treatment options. Our interdisciplinary team of biostatisticians, bioinformaticians, software developers and physician-scientists will address the analysis bottleneck with statistically and computationally sound methods. The SOUND consortium will (i) develop widely used and excellent bioinformatic and statistical methods and open source software for common but challenging tasks, including data pre-processing, data integration, statistical inference, visual presentation, and publication-quality reporting; (ii) introduce novel approaches to ground breaking multi-omics applications in oncology and medical genetics; (iii) develop interoperable data structures and software interfaces that enable seamless combination of tools; (iv) support a collaborative international academic and industry developer community; (v) enable rapid development and execution of high-quality software; (vi) lower the barrier to entry into this transdisciplinary field by providing simple, robust, easy-to-use solutions; and (vii) develop a training programme with regular courses and comprehensive online tutorials. Our aim is to create the de facto standard toolkit used in every clinical research lab for statistically informed analysis of personal multi-omic data. SOUND will increase research and innovation opportunities by reducing barriers of entry to genomic medicine across academic, healthcare and commercial sectors by translating in a rapid and efficient manner complex and innovative analytical approaches into modular, interoperable, reusable applications.

Field of science

  • /medical and health sciences/basic medicine/medical genetics
  • /natural sciences/biological sciences/genetics and heredity
  • /natural sciences/computer and information sciences/software
  • /medical and health sciences/clinical medicine/oncology

Call for proposal

H2020-PHC-2014-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action
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Coordinator

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany
Activity type
Research Organisations
EU contribution
€ 650 403,75

Participants (12)

FRED HUTCHINSON CANCER RESEARCH CENTER NON PROFIT CORPORATION

Participation ended

United States
EU contribution
€ 0
Address
Fairview Avenue 1100
98109 Seattle Wa
Activity type
Research Organisations
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
EU contribution
€ 0
Address
Raemistrasse 101
8092 Zuerich
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 323 261,25
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Participation ended

Germany
EU contribution
€ 38 179,45
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
INSTITUTO DE ENGENHARIA MECANICA
Portugal
EU contribution
€ 315 928,75
Address
Rua Rovisco Pais 1
1049 001 Lisboa
Activity type
Research Organisations
BEDATADRIVEN BV
Netherlands
EU contribution
€ 318 750
Address
Binckhorstlaan 36
2516 BE S Gravenhage
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITATSKLINIKUM HEIDELBERG

Participation ended

Germany
EU contribution
€ 0
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT ZURICH
Switzerland
EU contribution
€ 0
Address
Ramistrasse 71
8006 Zurich
Activity type
Higher or Secondary Education Establishments
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany
EU contribution
€ 331 000
Address
Ismaninger Strasse 22
81675 Muenchen
Activity type
Higher or Secondary Education Establishments
TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 274 570,55
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments
HEALTH RESEARCH INC
United States
EU contribution
€ 399 593,75
Address
Elm And Carlton Streets
14263 Buffalo
Activity type
Research Organisations
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 301 375
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations