Female cancer prediction using cervical omics to individualise screening and prevention

Project Information

FORECEE

Grant agreement ID: 634570

DOI 10.3030/634570

Project closed

EC signature date 27 March 2015

Start date 1 September 2015

End date 29 February 2020

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 7 994 746,25

EU contribution € 7 994 746,25

Coordinated by

UNIVERSITY COLLEGE LONDON
United Kingdom

Deliverables

Documents, reports (6)

Recommendations for screening policy from legal/regulatory/ethical and women’s perspective
Review on decision-analytic cost-effectiveness

Review on decision-analytic cost-effectiveness studies in women’s cancers (based on current screening/prevention strategies) analysis publication available

Cost-effectiveness in women’s cancer (based on WID test projections) analysis publication available
Leaflet and results from survey and public workshop results
Screening/prevention recommendations based on the WID test available
Scientific publication on the optimal delivery of risk-stratified screening, including consensus guidelines on implementation plan

Websites, patent fillings, videos etc. (3)

Project website
Multimedia presentation available
Formal presentation to the ESGO patient advocacy group (ENGAGe)

Formal presentation to the ESGO patient advocacy group ENGAGe

Publications

Peer reviewed articles (7)

Epigenetic Discrimination: Emerging Applications of Epigenetics Pointing to the Limitations of Policies Against Genetic Discrimination

Author(s): Charles Dupras, Lingqiao Song, Katie M. Saulnier, Yann Joly
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00202

Prediction models for endometrial cancer for the general population or symptomatic women: A systematic review

Author(s): Maaike Alblas, Kimberley B. Velt, Nora Pashayan, Martin Widschwendter, Ewout W. Steyerberg, Yvonne Vergouwe
Published in: Critical Reviews in Oncology/Hematology, Issue 126, 2018, Page(s) 92-99, ISSN 1040-8428
Publisher: Elsevier BV
DOI: 10.1016/j.critrevonc.2018.03.023

Ethical, Legal, and Regulatory Issues for the Implementation of Omics-Based Risk Prediction of Women’s Cancer: Points to Consider

Author(s): Emmanuelle Lévesque, Emily Kirby, Ineke Bolt, Bartha Maria Knoppers, Inez de Beaufort, Nora Pashayan, Martin Widschwendter
Published in: Public Health Genomics, 2018, Page(s) 1-8, ISSN 1662-4246
Publisher: S. Karger AG
DOI: 10.1159/000492663

Epigenome-based cancer risk prediction: rationale, opportunities and challenges

Author(s): Martin Widschwendter, Allison Jones, Iona Evans, Daniel Reisel, Joakim Dillner, Karin Sundström, Ewout W. Steyerberg, Yvonne Vergouwe, Odette Wegwarth, Felix G. Rebitschek, Uwe Siebert, Gaby Sroczynski, Inez D. de Beaufort, Ineke Bolt, David Cibula, Michal Zikan, Line Bjørge, Nicoletta Colombo, Nadia Harbeck, Frank Dudbridge, Anne-Marie Tasse, Bartha M. Knoppers, Yann Joly, Andrew E. Teschendorf
Published in: Nature Reviews Clinical Oncology, Issue 15/5, 2018, Page(s) 292-309, ISSN 1759-4774
Publisher: Nature Publishing Group
DOI: 10.1038/nrclinonc.2018.30

What do European women know about their female cancer risks and cancer screening? A cross-sectional online intervention survey in five European countries

Author(s): Odette Wegwarth, Martin Widschwendter, David Cibula, Karin Sundström, Rosalba Portuesi, Ines Lein, Felix G Rebitschek
Published in: BMJ Open, Issue 8/12, 2018, Page(s) e023789, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2018-023789

Integration of genetic and epigenetic markers for risk stratification: opportunities and challenges

Author(s): Nora Pashayan, Daniel Reisel, Martin Widschwendter
Published in: Personalized Medicine, Issue 13/2, 2016, Page(s) 93-95, ISSN 1741-0541
Publisher: Future Medicine Ltd.
DOI: 10.2217/pme.15.53

Serous tubal intraepithelial carcinoma (STIC) – clinical impact and management

Author(s): Vit Weinberger, Marketa Bednarikova, David Cibula, Michal Zikan
Published in: Expert Review of Anticancer Therapy, Issue 16/12, 2016, Page(s) 1311-1321, ISSN 1473-7140
Publisher: Future Drugs Ltd.
DOI: 10.1080/14737140.2016.1247699

Non-peer reviewed articles (1)

Autonomy Challenges in Epigenetic Risk-Stratified Cancer Screening: How Can Patient Decision Aids Support Informed Consent?

Author(s): Maaike Alblas, Maartje Schermer, Yvonne Vergouwe, Ineke Bolt
Published in: Journal of Personalized Medicine, Issue 9/1, 2019, Page(s) 14, ISSN 2075-4426
Publisher: Jourmal of Personalized Medicine
DOI: 10.3390/jpm9010014