Female cancer prediction using cervical omics to individualise screening and prevention

Deliverables

Recommendations for screening policy from legal/regulatory/ethical and women’s perspective

Review on decision-analytic cost-effectiveness

Review on decision-analytic cost-effectiveness studies in women’s cancers (based on current screening/prevention strategies) analysis publication available

Cost-effectiveness in women’s cancer (based on WID test projections) analysis publication available

Leaflet and results from survey and public workshop results

Screening/prevention recommendations based on the WID test available

Scientific publication on the optimal delivery of risk-stratified screening, including consensus guidelines on implementation plan

Project website

Multimedia presentation available

Formal presentation to the ESGO patient advocacy group (ENGAGe)

Formal presentation to the ESGO patient advocacy group ENGAGe

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Publications

Epigenetic Discrimination: Emerging Applications of Epigenetics Pointing to the Limitations of Policies Against Genetic Discrimination

Author(s): Charles Dupras, Lingqiao Song, Katie M. Saulnier, Yann Joly
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
DOI: 10.3389/fgene.2018.00202

Prediction models for endometrial cancer for the general population or symptomatic women: A systematic review

Author(s): Maaike Alblas, Kimberley B. Velt, Nora Pashayan, Martin Widschwendter, Ewout W. Steyerberg, Yvonne Vergouwe
Published in: Critical Reviews in Oncology/Hematology, Issue 126, 2018, Page(s) 92-99, ISSN 1040-8428
DOI: 10.1016/j.critrevonc.2018.03.023

Ethical, Legal, and Regulatory Issues for the Implementation of Omics-Based Risk Prediction of Women’s Cancer: Points to Consider

Author(s): Emmanuelle Lévesque, Emily Kirby, Ineke Bolt, Bartha Maria Knoppers, Inez de Beaufort, Nora Pashayan, Martin Widschwendter
Published in: Public Health Genomics, 2018, Page(s) 1-8, ISSN 1662-4246
DOI: 10.1159/000492663

Epigenome-based cancer risk prediction: rationale, opportunities and challenges

Author(s): Martin Widschwendter, Allison Jones, Iona Evans, Daniel Reisel, Joakim Dillner, Karin Sundström, Ewout W. Steyerberg, Yvonne Vergouwe, Odette Wegwarth, Felix G. Rebitschek, Uwe Siebert, Gaby Sroczynski, Inez D. de Beaufort, Ineke Bolt, David Cibula, Michal Zikan, Line Bjørge, Nicoletta Colombo, Nadia Harbeck, Frank Dudbridge, Anne-Marie Tasse, Bartha M. Knoppers, Yann Joly, Andrew E. Teschendorf
Published in: Nature Reviews Clinical Oncology, Issue 15/5, 2018, Page(s) 292-309, ISSN 1759-4774
DOI: 10.1038/nrclinonc.2018.30

What do European women know about their female cancer risks and cancer screening? A cross-sectional online intervention survey in five European countries

Author(s): Odette Wegwarth, Martin Widschwendter, David Cibula, Karin Sundström, Rosalba Portuesi, Ines Lein, Felix G Rebitschek
Published in: BMJ Open, Issue 8/12, 2018, Page(s) e023789, ISSN 2044-6055
DOI: 10.1136/bmjopen-2018-023789

Integration of genetic and epigenetic markers for risk stratification: opportunities and challenges

Author(s): Nora Pashayan, Daniel Reisel, Martin Widschwendter
Published in: Personalized Medicine, Issue 13/2, 2016, Page(s) 93-95, ISSN 1741-0541
DOI: 10.2217/pme.15.53

Serous tubal intraepithelial carcinoma (STIC) – clinical impact and management

Author(s): Vit Weinberger, Marketa Bednarikova, David Cibula, Michal Zikan
Published in: Expert Review of Anticancer Therapy, Issue 16/12, 2016, Page(s) 1311-1321, ISSN 1473-7140
DOI: 10.1080/14737140.2016.1247699

Autonomy Challenges in Epigenetic Risk-Stratified Cancer Screening: How Can Patient Decision Aids Support Informed Consent?

Author(s): Maaike Alblas, Maartje Schermer, Yvonne Vergouwe, Ineke Bolt
Published in: Journal of Personalized Medicine, Issue 9/1, 2019, Page(s) 14, ISSN 2075-4426
DOI: 10.3390/jpm9010014

Deliverables

Publications

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